Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475610 | 0.87 | MAPK14 (0.76) | MAPK14 | |
| SCHEMBL4473334 | 0.86 | MAPK14 (0.78) | MAPK14SMN1; SMN2 | |
| SCHEMBL4462584 | 0.86 | MAPK14 (0.85) | MAPK14SMN1; SMN2 | |
| SCHEMBL4478405 | 0.86 | MAPK14 (0.90) | MAPK14SMN1; SMN2 | |
| SCHEMBL4379163 | 0.83 | MAPK14 (1.00) | MAPK14SMN1; SMN2 | |
| SCHEMBL4467661 | 0.83 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL3522063 | 0.83 | PKM (0.53) | MAPK14PKMSMN1; SMN2LRRK2 | |
| SCHEMBL4387538 | 0.82 | MAPK14 (0.73) | MAPK14SMN1; SMN2 | |
| SCHEMBL4466494 | 0.82 | MAPK14 (1.00) | MAPK14PKMSMN1; SMN2 | |
| SCHEMBL4490267 | 0.81 | MAPK14 (0.77) | MAPK14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088033-A1 | Diaryl Substituted Pyridinones | DEVADAS BALEKUDRU | 2007-04-19 | — | — | US | claimed |
| US-20060211694-A1 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PHARMACIA CORPORATION, GLOBAL PATENT DEPARTMENT (US) | 2006-09-21 | — | — | US | claimed |
| US-20040058964-A1 | Substituted pyridinones | PHARMACIA LLC | 2004-03-25 | — | — | US | claimed |
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20070088033-A1 | Diaryl Substituted Pyridinones | DEVADAS BALEKUDRU | 2007-04-19 | — | — | US | disclosed |
| US-20070088033-A1 | Diaryl Substituted Pyridinones | DEVADAS BALEKUDRU | 2007-04-19 | — | — | US | disclosed |
| US-20070088033-A1 | Diaryl Substituted Pyridinones | DEVADAS BALEKUDRU | 2007-04-19 | — | — | US | disclosed |
| US-20060211694-A1 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PHARMACIA CORPORATION, GLOBAL PATENT DEPARTMENT (US) | 2006-09-21 | — | — | US | disclosed |
| US-7067540-B2 | Substituted pyridinones | PHARMACIA CORPORATION (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050176775-A1 | Substituted pyridinones | PHARMACIA CORPORATION | 2005-08-11 | — | — | US | disclosed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20040058964-A1 | Substituted pyridinones | PHARMACIA LLC | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058964-A1 | Substituted pyridinones | MAPK1, MAPK6, MAPK7 | MAPK14 41/4885PKM 543/4885SMN1; SMN2 1433/4885 |
| US-20060211694-A1 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | LTB4R2, LTB4R, MAPK1 | MAPK14 79/4885PKM 1683/4885SMN1; SMN2 4119/4885 |
| US-20050176775-A1 | Substituted pyridinones | MAPK1, MAPK6, MAP3K6 | MAPK14 53/4885PKM 451/4885SMN1; SMN2 1419/4885 |
| US-20070088033-A1 | Diaryl Substituted Pyridinones | MAPK1, MAPK6, MAP3K6 | MAPK14 46/4885PKM 991/4885SMN1; SMN2 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.