SCHEMBL44749

SCHEMBL44749

c1cnc(Oc2ncccn2)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
APAF1 O14727 1/20 0.52
LMNA P02545 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
RAB9A P51151 3/20 0.43
HDAC8 Q9BY41 1/20 0.39
HSP90AA1 P07900 1/20 0.39
MAPT P10636 2/20 0.38
NPC1 O15118 2/20 0.38
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL5711745 0.85 KMT2A (0.46) MEN1KMT2AAPAF1LMNASMN1; SMN2
SCHEMBL11133778 0.78 MEN1 (0.48) MEN1KMT2AAPAF1LMNASMN1; SMN2
SCHEMBL667594 0.76 MEN1 (0.64) MEN1KMT2AAPAF1LMNASMN1; SMN2
SCHEMBL9384543 0.74 KDM4E (0.50) MEN1KMT2AAPAF1LMNASMN1; SMN2
SCHEMBL28840343 0.73 MEN1 (0.65) MEN1KMT2AAPAF1LMNASMN1; SMN2
SCHEMBL13531346 0.73 MEN1 (0.48) MEN1KMT2AAPAF1LMNASMN1; SMN2
SCHEMBL153025 0.72
SCHEMBL316513 0.72
SCHEMBL7794820 0.72
SCHEMBL6044724 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) 2025-09-25 US claimed
WO-2025021115-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2025-01-30 WO claimed
CN-116157404-A Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof 诺华股份有限公司 2023-05-23 CN claimed
US-20220015371-A1 Compositions and Methods for Reducing Pesticide-Induced Plant Damage and Improving Plant Yield PNC BANK, NATIONAL ASSOCIATION 2022-01-20 US claimed
EP-3890491-A1 COMPOSITIONS AND METHODS FOR REDUCING PESTICIDE-INDUCED PLANT DAMAGE AND IMPROVING PLANT YIELD Cytozyme Laboratories, Inc. (US) 2021-10-13 EP claimed
CN-113226040-A Compositions and methods for reducing pesticide-induced plant damage and increasing plant yield 美国赛多美科技有限公司 2021-08-06 CN claimed
WO-2020118278-A1 COMPOSITIONS AND METHODS FOR REDUCING PESTICIDE-INDUCED PLANT DAMAGE AND IMPROVING PLANT YIELD CYTOZYME LABORATORIES, INC. (US) 2020-06-11 WO claimed
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines BASF SE (DE) 2019-07-02 US claimed
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2017-12-28 US claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
EP-1087664-B1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AG (DE) 2003-05-28 EP claimed
EP-1313369-A2 HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2003-05-28 EP claimed
EP-0861026-B1 SYNERGISTIC HERBICIDAL MIXTURES CONTAINING CYCLOHEXENONE OXIME ETHER BASF AG (DE) 2003-04-02 EP claimed
US-6534444-B1 3-heterocyclyl-substituted benzoyl derivative BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 US claimed
US-20020198106-A1 Synergistically active herbicidal mixtures LANDES MAX (DE) 2002-12-26 US claimed
JP-2002518303-A 2002-06-25 JP claimed
US-20020055435-A1 Herbicidal mixtures INTELLECTUAL PROPERTY DEPARTMENT (DE) 2002-05-09 US claimed
WO-2002015694-A2 HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2002-02-28 WO claimed
EP-1087664-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 2001-04-04 EP claimed
WO-1999065314-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1999-12-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 MEN1 4689/4885KMT2A 2661/4885APAF1 3233/4885
US-20020055435-A1 Herbicidal mixtures DDT, CYP2W1, CYP1B1 MEN1 3572/4885KMT2A 792/4885APAF1 2631/4885
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SCN8A, SCN11A, TRPV1 MEN1 3960/4885KMT2A 2442/4885APAF1 4560/4885
US-20020198106-A1 Synergistically active herbicidal mixtures DDT, RIN1, RER1 MEN1 2693/4885KMT2A 4003/4885APAF1 1800/4885
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 MEN1 4689/4885KMT2A 2661/4885APAF1 3233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.