SCHEMBL4474908

SCHEMBL4474908

C=Cc1ccc(C(=O)O)c(N)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 5/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MCL1 Q07820 2/20 0.48
TDP1 Q9NUW8 3/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX15 P16050 1/20 0.47
PPM1B O75688 1/20 0.46
IDO1 P14902 1/20 0.44
TBK1 Q9UHD2 1/20 0.44
KMT2A Q03164 3/20 0.42
GFER P55789 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
MAPT P10636 4/20 0.41
PTPN1 P18031 3/20 0.41
MEN1 O00255 2/20 0.41
THRB P10828 2/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13083829 0.85 KMT2A (0.57) ALDH1A1KDM4EMCL1TDP1CYP3A4
SCHEMBL29393716 0.84 PTPN1 (0.55) ALDH1A1KDM4EHPGDHSD17B10MCL1
SCHEMBL3899360 0.83 HDAC3 (0.51) ALDH1A1KDM4EHPGDHSD17B10MCL1
SCHEMBL11731637 0.82 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10MCL1
SCHEMBL220169 0.82 MCL1 (0.51) ALDH1A1HPGDHSD17B10MCL1TDP1
Hydrochloric Acid SCHEMBL6544646 0.79 HDAC2 (0.45) MCL1IDO1MAPTPOLBGAA
SCHEMBL1813719 0.78 PTPN1 (0.62) ALDH1A1KDM4EHPGDHSD17B10MCL1
SCHEMBL21071933 0.78 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10MCL1
SCHEMBL14321519 0.77 PTPN1 (0.50) ALDH1A1KDM4EMCL1TBK1PTPN1
SCHEMBL940632 0.77 MCL1 (0.48) ALDH1A1HSD17B10MCL1TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0896876-B1 FUNCTIONAL MEMBER HAVING MOLECULAR FILM ON THE SURFACE AND PROCESS FOR THE PRODUCTION THEREOF PANASONIC CORP (JP) 2009-01-21 EP claimed
EP-4318681-A1 HYDROPHILIC POLYMER AND MANUFACTURING METHOD THEREFOR, AND LITHIUM SECONDARY BATTERY COMPRISING HYDROPHILIC POLYMER Contemporary Amperex Technology Co., Limited (CN) 2024-02-07 EP disclosed
CN-115151523-A Metal-organic structure having carboxylate ion having terphenyl skeleton as ligand 学校法人立教学院 2022-10-04 CN disclosed
CN-114072454-A Metal-organic structure having terephthalic acid-based ligand 学校法人立教学院 2022-02-18 CN disclosed
CN-113811525-A Metal organic structure 学校法人立教学院 2021-12-17 CN disclosed
WO-2020230756-A1 METAL-ORGANIC STRUCTURAL BODY 学校法人立教学院 2020-11-19 WO disclosed
CN-104379568-A Quinazolinedione derivative CHUGAI PHARMACEUTICAL CO LTD 2015-02-25 CN disclosed
CN-101448917-B Liquid-crystalline composition with improved adhesion, liquid-crystal film comprising the composition, and liquid-crystal display element employing the film NIPPON OIL CORP 2013-04-10 CN disclosed
CN-101448917-A Liquid-crystalline composition with improved adhesion, liquid-crystal film comprising the composition, and liquid-crystal display element employing the film NIPPON OIL CORP (JP) 2009-06-03 CN disclosed
EP-0896876-B1 FUNCTIONAL MEMBER HAVING MOLECULAR FILM ON THE SURFACE AND PROCESS FOR THE PRODUCTION THEREOF PANASONIC CORP (JP) 2009-01-21 EP disclosed
CN-1522268-A Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display 新日本石油株式会社 2004-08-18 CN disclosed
US-20040070309-A1 Structure containing organic molecular layers and its use MATSUSHITA ELECTRICAL INDUSTRIAL CO. (JP) 2004-04-15 US disclosed
EP-0849003-B1 Organic ultra-thin film and method for making the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2004-03-31 EP disclosed
US-6621191-B1 Structure containing organic molecular layer and use thereof MATSUSHITA ELECTRIC INDUSTRIAL CO., INC. (JP) 2003-09-16 US disclosed
EP-1331042-A2 Organic ultra-thin film and method for making the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-07-30 EP disclosed
EP-1331043-A2 Organic ultra-thin film and method for making the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-07-30 EP disclosed
US-6203919-B1 DIELECTRICS, MULTILAYER CONDUCTOR SUBSTRATES WITH DITHIOTRIAZINES AND TRANSITION METAL SULFUR BONDS AND SECOND LAYER MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-03-20 US disclosed
EP-0849744-B1 Insulating film and method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2000-05-10 EP disclosed
EP-0849744-A2 Insulating film and method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0849003-A1 Organic ultra-thin film and method for making the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-06-24 EP disclosed