Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499011 | 0.86 | GAA (0.46) | PPARGMAPTLMNAKMT2ARAB9A | |
| SCHEMBL4329791 | 0.72 | LMNA (0.44) | MAPTLMNAKMT2ATDP1RAB9A | |
| SCHEMBL4499008 | 0.71 | PPARG (0.48) | PPARGMAPTLMNAKMT2ATDP1 | |
| SCHEMBL14281812 | 0.71 | CA12 (0.67) | MAPTLMNAKMT2ATDP1RAB9A | |
| SCHEMBL4328015 | 0.70 | NPC1 (0.47) | MAPTLMNAKMT2ATDP1RAB9A | |
| SCHEMBL4474935 | 0.70 | PPARG (0.48) | PPARGMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4341658 | 0.69 | MAPT (0.48) | MAPTLMNAKMT2ARAB9ASMN1; SMN2 | |
| Benzyl Benzoate SCHEMBL11156612 | 0.68 | TDP1 (0.79) | MAPTLMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL4327192 | 0.68 | CYP1A2 (0.56) | PPARGMAPTLMNAKMT2ARAB9A | |
| SCHEMBL4335538 | 0.68 | KMT2A (0.45) | MAPTKMT2ATDP1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |