Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.46 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.46 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.46 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440185 | 1.00 | POLM (0.46) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL28128474 | 1.00 | POLM (0.46) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL9567322 | 1.00 | POLM (0.46) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL29285072 | 1.00 | POLM (0.46) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL1756481 | 1.00 | POLM (0.46) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL30543 | 0.98 | KMT2A (0.44) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL16552524 | 0.94 | KMT2A (0.49) | KMT2ASMN1; SMN2HDAC1HDAC11HDAC8 | |
| SCHEMBL5342899 | 0.90 | ALDH1A1 (0.49) | KMT2ASMN1; SMN2HDAC1KDM4EMEN1 | |
| SCHEMBL8327418 | 0.87 | KMT2A (0.47) | KMT2ASMN1; SMN2KDM4EMEN1RECQL | |
| SCHEMBL27766082 | 0.86 | HPGD (0.55) | SMN1; SMN2HDAC1HDAC11HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097706-A1 | SYSTEM FOR REMOVING PROTEIN BOUND UREMIC TOXINS DURING HEMODIALYSIS | UNIVERSITY OF WASHINGTON (US) | 2024-05-10 | — | — | WO | disclosed |
| EP-2032623-A2 | FILMS AND PARTICLES | The Trustees of the Boston University (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007140483-A2 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2007-12-06 | — | — | WO | disclosed |