SCHEMBL8327418

SCHEMBL8327418

CCCC(=O)Oc1cccs1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
ALDH1A1 P00352 6/20 0.47
MAPT P10636 2/20 0.47
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
BCL9 O00512 1/20 0.41
CTNNB1 P35222 1/20 0.41
PLA2G1B P04054 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
LMNA P02545 4/20 0.40
POLB P06746 3/20 0.40
MEN1 O00255 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALOX15 P16050 1/20 0.40
ADORA2A P29274 2/20 0.39
ADORA1 P30542 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921015 0.98 KMT2A (0.46) KMT2AALDH1A1MAPTMMP1MMP2
SCHEMBL16552524 0.90 KMT2A (0.49) KMT2AALDH1A1MAPTMMP1MMP2
SCHEMBL5352083 0.89 MMP1 (0.47) KMT2AALDH1A1MAPTMMP1MMP2
SCHEMBL30543 0.88 KMT2A (0.44) KMT2AALDH1A1MMP1MMP2MMP9
SCHEMBL1756481 0.87 POLM (0.46) KMT2AALDH1A1LMNAPOLBMEN1
SCHEMBL4474985 0.87 POLM (0.46) KMT2AALDH1A1LMNAPOLBMEN1
SCHEMBL28128474 0.87 POLM (0.46) KMT2AALDH1A1LMNAPOLBMEN1
SCHEMBL9567322 0.87 POLM (0.46) KMT2AALDH1A1LMNAPOLBMEN1
SCHEMBL4440185 0.87 POLM (0.46) KMT2AALDH1A1LMNAPOLBMEN1
SCHEMBL29285072 0.87 POLM (0.46) KMT2AALDH1A1LMNAPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1161962-A Sulphonic-acid-amide derivative KONO PHARMACEUTICAL IND K K (JP) 1997-10-15 CN claimed
CN-108299363-B A kind of synthetic method of 3- benzene sulfonyl class coumarin kind compound 青岛农业大学 2019-10-08 CN disclosed
CN-108299363-A A kind of synthetic method of 3- benzene sulfonyls class coumarin kind compound 青岛农业大学 2018-07-20 CN disclosed
CN-107722049-A A kind of preparation and its application of novel ionic double-core schiff bases titanium complex 山西医科大学 2018-02-23 CN disclosed
CN-107656423-A Photosensitive resin composition and color filter containing the same 株式会社LG化学 2018-02-02 CN disclosed
CN-106082765-A A kind of concrete admixture and preparation method thereof 南京晶云化工有限公司 2016-11-09 CN disclosed
US-9147843-B2 Organic semiconductor material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-09-29 US disclosed
WO-2015096797-A1 POLYMER/FULLERENE FORMATIONS AND THEIR USE IN ELECTRONIC/PHOTONIC DEVICES THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2015-07-02 WO disclosed
US-20150065671-A1 ORGANIC SEMICONDUCTOR MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-05 US disclosed
US-20140227515-A1 GAS BARRIER FILM MITSUI CHEMICALS TOHCELLO, INC. (JP) 2014-08-14 US disclosed
CN-1226910-A Process for preparing polymer/bitumen compositions and their use in coatings ELF ANTAR FRANCE (FR) 1999-08-25 CN disclosed
EP-0789571-A4 CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE MERCK & CO INC (US) 1999-04-14 EP disclosed
CN-1177960-A 6-substituted pyrazolo (3, 4 -d) pyrimidin -4 ones and compositions and methods of use thereof SANOFI WINTHROP INC (US) 1998-04-01 CN disclosed
CN-1161962-A Sulphonic-acid-amide derivative KONO PHARMACEUTICAL IND K K (JP) 1997-10-15 CN disclosed
EP-0789571-A1 CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE Merck & Co., Inc. (US) 1997-08-20 EP disclosed
US-5629322-A TREATMENT OF NEURODEGENERATIVE DISORDERS, DISORDERS OF GASTROINTESTINAL MOTILITY AND INFLAMMATION MERCK & CO., INC. (US) 1997-05-13 US disclosed
WO-1996014844-A1 CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE MERCK & CO., INC. (US) 1996-05-23 WO disclosed
CN-1075478-A Azole derivative herbicides and sterilant SCHERING AGROCHEMICALS LTD (GB) 1993-08-25 CN disclosed
CN-1073174-A Hete rocyclic derivatives ICI PLC (GB) 1993-06-16 CN disclosed
US-4532186-A Electrically insulating layer with resistance layer of nickel-tin alloy containing sulfur bonded to one surface, highly conductive layer bonded to resistance layer NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-07-30 US disclosed