Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 17/20 | 0.53 |
| ▸ | PGR | P06401 | 14/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291812 | 0.89 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL4467422 | 0.88 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL13754608 | 0.88 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL5798431 | 0.87 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL290888 | 0.84 | NR3C1 (0.75) | NR3C1NR3C2PGR | |
| SCHEMBL292222 | 0.83 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL292301 | 0.83 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL291462 | 0.83 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL4161029 | 0.82 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL4487196 | 0.82 | NR3C1 (0.58) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |