Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 19/20 | 0.52 |
| ▸ | PGR | P06401 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475160 | 0.88 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL13754608 | 0.85 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL291812 | 0.85 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL5798431 | 0.84 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL290888 | 0.81 | NR3C1 (0.75) | NR3C1NR3C2PGR | |
| SCHEMBL4487196 | 0.81 | NR3C1 (0.58) | NR3C1NR3C2PGR | |
| SCHEMBL292222 | 0.81 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL292872 | 0.80 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL292177 | 0.80 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL291462 | 0.80 | NR3C1 (0.52) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162321-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-08-19 | — | — | US | claimed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162321-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, NR3C2, MC2R | NR3C1 1/4885NR3C2 2/4885PGR 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.