Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4463701 | 0.95 | KDM4E (0.30) | HTR6 | |
| Hydrochloric Acid SCHEMBL4470117 | 0.93 | HTR6 (0.31) | HTR6 | |
| Hydrochloric Acid SCHEMBL4463820 | 0.89 | HTR6 (0.30) | HTR6 | |
| Hydrochloric Acid SCHEMBL4466977 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL4478983 | 0.84 | HTR6 (0.30) | HTR6 | |
| Hydrochloric Acid SCHEMBL4462924 | 0.83 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL4459355 | 0.82 | HTR6 (0.43) | HTR6 | |
| Hydrochloric Acid SCHEMBL4469885 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL4463095 | 0.79 | HTR6 (0.32) | HTR6 | |
| Hydrochloric Acid SCHEMBL6061243 | 0.79 | HTR6 (0.30) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671983-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 2006-06-21 | — | — | EP | claimed |
| EP-1671983-B1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA SA (ES) | 2009-02-25 | — | — | EP | disclosed |
| EP-1671983-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 2006-06-21 | — | — | EP | disclosed |