SCHEMBL4476194

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4477428	0.88	CNR2 (0.64)	CNR2P2RX7SIGMAR1S1PR1S1PR5
	SCHEMBL4465986	0.86	CNR2 (0.61)	CNR2P2RX7GRM2PDE2ACHRNA7
	SCHEMBL4751823	0.85	CNR2 (0.55)	CNR2P2RX7GRM2PDE2ACHRNA7
	SCHEMBL4468418	0.84	CNR2 (0.64)	CNR2P2RX7S1PR1ATM
	SCHEMBL4476472	0.83	CNR2 (0.57)	CNR2P2RX7GRM2PDE2ACHRNA7
	SCHEMBL4476140	0.83	CNR2 (0.52)	CNR2SIGMAR1
	SCHEMBL4486819	0.83	CNR2 (0.52)	CNR2SIGMAR1
	SCHEMBL4476137	0.83	CNR2 (0.52)	CNR2SIGMAR1
	SCHEMBL4694748	0.81	CNR2 (0.46)	CNR2P2RX7SIGMAR1CYP2D6
	SCHEMBL27489861	0.81	P2RX7 (0.50)	CNR2P2RX7SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.