Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2164246 | 0.85 | HDAC8 (0.39) | ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL4469432 | 0.81 | GPR3 (0.43) | GPR3KCNH2ACHE | |
| SCHEMBL11256315 | 0.81 | NPSR1 (0.39) | KCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL30330386 | 0.81 | GPR3 (0.43) | GPR3KCNH2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL9314025 | 0.81 | GPR3 (0.43) | GPR3KCNH2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL6421880 | 0.81 | GPR3 (0.43) | GPR3KCNH2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL8716929 | 0.81 | GPR3 (0.43) | GPR3KCNH2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL320422 | 0.79 | HDAC8 (0.62) | GPR3KCNH2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL31105615 | 0.79 | HDAC8 (0.62) | GPR3KCNH2ACHE | |
| SCHEMBL29502455 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970512-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-04-30 | — | — | US | disclosed |
| US-20220056066-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2022-02-24 | — | — | US | disclosed |
| US-11117920-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-09-14 | — | — | US | disclosed |
| US-11028114-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-06-08 | — | — | US | disclosed |
| US-20190345187-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-11-14 | — | — | US | disclosed |
| US-10323057-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-06-18 | — | — | US | disclosed |
| EP-3055030-B1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | UNIV ILLINOIS (US) | 2018-05-02 | — | — | EP | disclosed |
| EP-3055030-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | The Board of Trustees of the University of Illinois (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20160215012-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2016-07-28 | — | — | US | disclosed |
| WO-2015054148-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | RHODIA CHIMIE (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-0786692-B1 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK CO (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-0786690-B1 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK CO (US) | 2000-03-22 | — | — | EP | disclosed |
| US-6010841-A | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK COMPANY (US) | 2000-01-04 | — | — | US | disclosed |
| US-5747235-A | SILVER HALIDE ADSORBERS IN EMULSIONS FOR PHOTOGRAPHIC FILMS | EASTMAN KODAK COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0786690-A2 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0786692-A1 | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity | EASTMAN KODAK COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5541000-A | Latent, thermal cure accelerators for epoxy-aromatic amine resins having lowered peak exotherms | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0719293-A1 | LATENT, THERMAL CURE ACCELERATORS FOR EPOXY-AROMATIC AMINE RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995005411-A2 | LATENT, THERMAL CURE ACCELERATORS FOR EPOXY-AROMATIC AMINE RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | AHR, CYP2E1, CYP2F1 | GPR3 541/4885KCNH2 890/4885ACHE 3533/4885 |
| US-20220056066-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
| US-20160215012-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
| US-20190345187-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
| US-10323057-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
| US-11028114-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
| US-11117920-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
| US-11970512-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | GPR3 2795/4885KCNH2 3139/4885ACHE 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.