Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
| ▸ | THRA | P10827 | 7/20 | 0.61 |
| ▸ | THRB | P10828 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126722 | 0.92 | THRA (0.65) | RARBTHRATHRBALDH1A1MEN1 | |
| SCHEMBL75643 | 0.92 | THRA (0.65) | RARBTHRATHRBALDH1A1MEN1 | |
| SCHEMBL10666525 | 0.92 | THRA (0.65) | RARBTHRATHRBALDH1A1MEN1 | |
| SCHEMBL5187964 | 0.88 | PLK1 (0.60) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL1404028 | 0.83 | RARB (0.67) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL2564366 | 0.83 | RARB (0.67) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL13950912 | 0.83 | RARB (0.67) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL9693784 | 0.82 | RARB (0.65) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL967078 | 0.82 | HSD17B10 (0.67) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL181230 | 0.82 | RARB (0.89) | RARBPLK1THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569646-B1 | Group IVB transition metal compounds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-08-04 | — | — | US | claimed |
| US-6617466-B1 | Having a heteroatom ligand containing an element with a coordination number of three from Group V A or a coordination number of two from Group VI A attached to the ring through a hydrocarbylene, silane or germanium group | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-09-09 | — | — | US | claimed |
| US-7569646-B1 | Group IVB transition metal compounds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-RE40234-E1 | Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system | EXXONMOBIL CHEMICAL PATENTS, INC. | 2008-04-08 | — | — | US | disclosed |
| US-7342039-B2 | Substituted indole oximes | WYETH (US) | 2008-03-11 | — | — | US | disclosed |
| EP-1110974-B1 | Method for preparing a supported activator component | EXXONMOBIL CHEM PATENTS INC (US) | 2007-11-28 | — | — | EP | disclosed |
| US-7205364-B1 | Olefin polymerization catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20060178491-A1 | Olefin polymerization catalysts | CANICH JO ANN M | 2006-08-10 | — | — | US | disclosed |
| EP-1667670-A1 | 4-(1H-INDOL-3-YL-METHYLIDENEAMINOXY-PROPOXY)-BENZOIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PAI-1 INHIBITORS FOR THE TREATMENT OF IMPAIREMENT OF THE FIBRINOLYTIC SYSTEM AND OF THROMBISIS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-7041841-B1 | Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-20050119326-A1 | Substituted aryloximes | WYETH (US) | 2005-06-02 | — | — | US | disclosed |
| US-6617466-B1 | Having a heteroatom ligand containing an element with a coordination number of three from Group V A or a coordination number of two from Group VI A attached to the ring through a hydrocarbylene, silane or germanium group | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-09-09 | — | — | US | disclosed |
| EP-0548277-B1 | PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0275077-B1 | ANTHRAQUINONE COMPOUNDS AND POLARIZING FILM CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4921959-A | POLARIZING FILMS, DICHROMISM | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1990-05-01 | — | — | US | disclosed |
| US-4841057-A | POLARIZING FILMS; HIGH DICHROISM, PERFORMANCE | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0275077-A1 | Anthraquinone compounds and polarizing film containing the same | MITSUBISHI KASEI CORPORATION (JP) | 1988-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119326-A1 | Substituted aryloximes | IDO2, TDO2, IDO1 | RARB 2989/4885PLK1 2371/4885THRA 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.