Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819487 | 1.00 | LMNA (0.45) | LMNACCR5CYP2D6TAAR1CYP1A2 | |
| SCHEMBL11992984 | 1.00 | LMNA (0.45) | LMNACCR5CYP2D6TAAR1CYP1A2 | |
| SCHEMBL813771 | 0.89 | CYP1A2 (0.50) | LMNACYP2D6TAAR1CYP1A2PKM | |
| SCHEMBL9246055 | 0.84 | CYP1A2 (0.42) | LMNACYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL1169267 | 0.84 | CYP1A2 (0.42) | LMNACYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL5895589 | 0.84 | LMNA (0.46) | LMNACCR5CYP2D6TAAR1CYP1A2 | |
| SCHEMBL6871261 | 0.84 | LMNA (0.46) | LMNACCR5CYP2D6TAAR1CYP1A2 | |
| SCHEMBL16352603 | 0.83 | LMNA (0.42) | LMNACCR5CYP2D6TAAR1CYP1A2 | |
| SCHEMBL169508 | 0.81 | LMNA (0.56) | LMNACCR5CYP2D6TAAR1MIF | |
| SCHEMBL7782492 | 0.81 | HPGD (0.41) | LMNACYP2D6CYP1A2PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11199890-A | — | — | None | — | — | JP | disclosed |
| US-9790436-B2 | Methods and systems for processing cellulosic biomass | SHELL OIL COMPANY (US) | 2017-10-17 | — | — | US | disclosed |
| EP-3201237-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSIC BIOMASS | Shell Internationale Research Maatschappij B.V. (NL) | 2017-08-09 | — | — | EP | disclosed |
| EP-3201257-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSIC BIOMASS | Shell Internationale Research Maatschappij B.V. (NL) | 2017-08-09 | — | — | EP | disclosed |
| US-20160097000-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSIC BIOMASS | SHELL OIL COMPANY | 2016-04-07 | — | — | US | disclosed |
| WO-2016053948-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSIC BIOMASS | SHELL OIL COMPANY (US) | 2016-04-07 | — | — | WO | disclosed |
| WO-2016053957-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSIC BIOMASS | SHELL OIL COMPANY (US) | 2016-04-07 | — | — | WO | disclosed |
| WO-2016053962-A1 | METHODS AND SYSTEMS FOR PROCESSING CELLULOSIC BIOMASS | SHELL OIL COMPANY (US) | 2016-04-07 | — | — | WO | disclosed |
| US-20120309963-A1 | 5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120108566-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |
| JP-H11199890-A | USE OF 1-METHOXY-2-METHYL-3-PHENYLPROPANE, 1-(2-METHOXYPROPYL)-4-METHYLBENZENE AND 3-METHOXY-2,2,3-TRIMETHYL-1-PHENYLBUTANE IN PERFUME | FIRMENICH SA | 1999-07-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309963-A1 | 5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS | MAP3K5, CDK5, MAP4K2 | LMNA 2490/4885CCR5 910/4885CYP2D6 2558/4885 |
| US-20120108566-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | JAK2, JAK1, NADK | LMNA 2451/4885CCR5 1634/4885CYP2D6 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.