Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782494 | 1.00 | HPGD (0.41) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL813771 | 0.87 | CYP1A2 (0.50) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL1169267 | 0.83 | CYP1A2 (0.42) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL9246055 | 0.83 | CYP1A2 (0.42) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL11992984 | 0.81 | LMNA (0.45) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL4476581 | 0.81 | LMNA (0.45) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL12819487 | 0.81 | LMNA (0.45) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL9452584 | 0.79 | HTR2A (0.43) | TSHRCYP2D6CYP1A2SMN1; SMN2PKM | |
| SCHEMBL1259372 | 0.79 | GABBR2 (0.50) | CYP2D6CYP1A2SMN1; SMN2PKMNPSR1 | |
| SCHEMBL8401102 | 0.79 | CYP1A2 (0.44) | HPGDTSHRCYP2D6CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1082944-C | Novel aspartyl amide derivative and sweetener | AJINOMOTO GENERAL FOODS K K (JP) | 2002-04-17 | — | — | CN | disclosed |
| EP-0784050-B1 | Novel aspartylamide derivatives and sweeteners | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6010733-A | ARTIFICIAL SWEETENER | AJINOMOTO CO., INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| CN-1163261-A | Novel aspartyl amide derivative and sweetener | AJINOMOTO GENERAL FOODS INC (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0784050-A1 | Novel aspartylamide derivatives and sweeteners | Ajinomoto Co., Inc. (JP) | 1997-07-16 | — | — | EP | disclosed |