Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456760 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22EGLN1 | |
| SCHEMBL28346537 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22EGLN1 | |
| SCHEMBL13732745 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22EGLN1 | |
| SCHEMBL100416 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22EGLN1 | |
| SCHEMBL27709413 | 0.97 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL20594222 | 0.97 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL14472237 | 0.97 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL429060 | 0.97 | LMNA (0.53) | TSHRLMNANFKB1PMP22EGLN1 | |
| Ammonia Solution, Strong SCHEMBL28812365 | 0.95 | TSHR (0.57) | TSHRLMNANFKB1PMP22GPR84 | |
| Glutarate SCHEMBL28269346 | 0.95 | TSHR (0.57) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115701464-B | Super-hydrophobic finishing agent and preparation method and application thereof | 江苏金太阳纺织科技股份有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-115418148-A | Organic reversible thermochromic exterior wall coating and preparation method thereof | 中机铸材科技（福建）有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-113981713-A | Method for dyeing real silk fabric by using natural dye | 达利(中国)有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-117881401-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117858870-A | Preparation of P2X3 antagonists | 葛兰素史密斯克莱知识产权(第3号)有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117597345-A | Heterocyclic derivatives as CaMKK2 inhibitors | 百时美施贵宝公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113981713-B | Method for dyeing real silk fabric by adopting natural dye | 达利(中国)有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117241797-A | Method for treating prostate cancer | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-111566089-B | IRE1 small molecule inhibitors | 康奈尔大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115605209-A | NLRP3 modulators | 祖玛珍生物科学有限公司（GB） | 2023-01-13 | — | — | CN | disclosed |
| CN-115484958-A | Combination of LSD-1 inhibitor and nivolumab for the treatment of SCLC or SQNSCLC | 赛尔基因昆蒂赛尔研究公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-1438996-A | Bicyclic cyclohexylamines and their use NMDA receptor antogonists | WARNER LAMBERT CO (US) | 2003-08-27 | — | — | CN | disclosed |
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
| CN-1425008-A | 3-aminoquinazolin-2, 4-dione antibacterial agents | WARNER LAMBERT CO (US) | 2003-06-18 | — | — | CN | disclosed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | disclosed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |
| US-5567767-A | UNSATURATED POLYESTER, DI(METH) ACRYLATE OF ALKYLOXYLATED BISPHENOL A, AND VINYL TOLUENE | ARISTECH CHEMICAL CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0359796-A1 | THERMOSETTING COMPOSITION FROM MALEIMIDE, OLEFINIC MONOMER AND UNSATURATED POLYESTER. | ARISTECH CHEMICAL CORP (US) | 1990-03-28 | — | — | EP | disclosed |
| WO-1989008670-A1 | THERMOSETTING COMPOSITION FROM MALEIMIDE, OLEFINIC MONOMER AND UNSATURATED POLYESTER | ARISTECH CHEMICAL CORPORATION (US) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | ABCC1, RPS6KA1, SIGMAR1 | TSHR 2363/4885LMNA 3614/4885NFKB1 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.