Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472639 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL4481183 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL4462762 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL4473586 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL4472806 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL4474007 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL2883946 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL2883172 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| SCHEMBL2880905 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BKDM1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL2883295 | 0.86 | HTR2C (0.56) | HTR2CHTR2AHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667972-B1 | DIASTEREOMERS OF 4-ARYLOXY-3-HYDROXYPIPERIDINES | BRENTWOOD EQUITIES LTD (GB) | 2013-06-19 | — | — | EP | disclosed |
| US-7504419-B2 | Diastereomers of 4-aryloxy-3-hydroxypiperidines | RATTAN BALVINDER SINGH | 2009-03-17 | — | — | US | disclosed |
| EP-1667972-A2 | DIASTEREOMERS OF 4-ARYLOXY-3-HYDROXYPIPERIDINES | BRENTWOOD EQUITIES LTD. (GB) | 2006-06-14 | — | — | EP | disclosed |
| US-20050203136-A1 | Diastereomers of 4-aryloxy-3-hydroxypiperidines | RATTAN BALVINDER S (GB) | 2005-09-15 | — | — | US | disclosed |
| WO-2005023767-A2 | DIASTEREOMERS OF 4-ARYLOXY-3-HYDROXYPIPERIDINES | BRENTWOOD EQUITIES LTD. (US) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203136-A1 | Diastereomers of 4-aryloxy-3-hydroxypiperidines | HTR2C, HTR4, HTR5A | HTR2C 1/4885HTR2A 7/4885HTR2B 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.