Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 13/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479046 | 1.00 | ADRB1 (0.49) | ADRB1ADRB3PTGS2EGFRADRB2 | |
| SCHEMBL4459818 | 0.87 | BCL2L1 (0.44) | EGFRBCL2L1MCL1 | |
| SCHEMBL4459823 | 0.87 | BCL2L1 (0.44) | EGFRBCL2L1MCL1 | |
| Hydrochloric Acid SCHEMBL4462352 | 0.83 | ADRB1 (0.68) | ADRB1ADRB3PTGS2EGFRADRB2 | |
| Hydrochloric Acid SCHEMBL4462356 | 0.83 | ADRB1 (0.68) | ADRB1ADRB3PTGS2EGFRADRB2 | |
| SCHEMBL4462089 | 0.72 | ADRB3 (0.59) | ADRB1ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL4463369 | 0.71 | ADRB1 (0.70) | ADRB1ADRB3ADRB2 | |
| SCHEMBL4475815 | 0.68 | KDM4E (0.48) | ADRB1ADRB3 | |
| SCHEMBL4475818 | 0.68 | KDM4E (0.48) | ADRB1ADRB3 | |
| SCHEMBL25260556 | 0.67 | MMP2 (0.49) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629366-B2 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20060100252-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-11 | — | — | US | disclosed |
| US-7037938-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2006-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100252-A1 | Aminoalcohol derivatives | H1-0, CHRM2, CHRM1 | ADRB1 39/4885ADRB3 130/4885PTGS2 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.