Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.80 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.76 |
| ▸ | PPARG | P37231 | 7/20 | 0.76 |
| ▸ | PPARD | Q03181 | 7/20 | 0.76 |
| ▸ | PPARA | Q07869 | 7/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.76 |
| ▸ | TSHR | P16473 | 4/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.76 |
| ▸ | FABP4 | P15090 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | TLR2 | O60603 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.76 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL1682245 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL28534845 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL6559646 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL11054069 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL15603224 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL25269213 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL10489552 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Dodecanoate SCHEMBL9748587 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Myristic Acid SCHEMBL6567029 | 0.98 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Decanoic Acid SCHEMBL1682224 | 0.95 | GPR84 (0.77) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517993-B2 | Pioglitazone hydrochloride | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-04-14 | — | — | US | disclosed |
| US-20070043094-A1 | Pioglitazone hydrochloride | ETHICON ENDO-SURGERY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-7135485-B2 | Crystallization by dissolving in solvent, mixing with water, precipitation; antihyperglycemic agents | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-11-14 | — | — | US | disclosed |
| US-20030139603-A1 | Pioglitazone hydrochloride | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-07-24 | — | — | US | disclosed |
| WO-2003026586-A2 | PIOGLITAZONE HYDROCHLORIDE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-04-03 | — | — | WO | disclosed |
| US-5866306-A | POLYALKYLPHENYLSILANE | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-02-02 | — | — | US | disclosed |
| US-5204226-A | N-sulfosuccinimides as photodegradation promoters for making integrated circuits using positive photoresists | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0502662-A1 | Process for use of photosensitive polysilanes as a photoresist | International Business Machines Corporation (US) | 1992-09-09 | — | — | EP | disclosed |
| EP-0502677-A1 | Photosensitizers for polysilanes | International Business Machines Corporation (US) | 1992-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043094-A1 | Pioglitazone hydrochloride | PPARA, GLP1R, PPARD | AKR1B1 1577/4885GPR84 1768/4885PPARG 5/4885 |
| US-20030139603-A1 | Pioglitazone hydrochloride | PPARA, GLP1R, PPARD | AKR1B1 1577/4885GPR84 1768/4885PPARG 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.