SCHEMBL44800

SCHEMBL44800

CC(SCc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 2/20 0.56
ATM Q13315 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPSR1 Q6W5P4 1/20 0.55
PPARG P37231 1/20 0.54
PPARA Q07869 1/20 0.54
LMNA P02545 1/20 0.54
ALDH1A1 P00352 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 1/20 0.52
EPHX1 P07099 2/20 0.50
KDM4E B2RXH2 1/20 0.49
THRB P10828 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL9833196 0.93 POLB (0.51) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL15141726 0.86 L3MBTL1 (0.55) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL7873176 0.85 EPHX1 (0.70) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL9857113 0.85 POLB (0.54) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL7396452 0.85 EPHX1 (0.70) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL7716568 0.85 EPHX1 (0.51) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL15733043 0.84 MAOB (0.54) L3MBTL1PPARGPPARALMNA
SCHEMBL11769885 0.83 PPARG (0.54) L3MBTL1POLBATMSMN1; SMN2NPSR1
SCHEMBL31720458 0.83 EPHX1 (0.49) L3MBTL1POLBATMSMN1; SMN2LMNA
SCHEMBL9741104 0.82 L3MBTL1 (0.55) L3MBTL1POLBATMSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118356531-A Antibacterial lubricating coating, medical instrument and preparation method thereof 广州保瑞医疗技术有限公司 2024-07-19 CN disclosed
EP-2666814-B1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2018-03-14 EP disclosed
EP-2629151-B1 CHARGING MEMBER CANON KK (JP) 2017-03-08 EP disclosed
CN-102566269-B Coloured composition, colour filter and display element JSR株式会社 2016-06-15 CN disclosed
EP-2666814-A1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2013-11-27 EP disclosed
EP-2629151-A1 ELECTRIFICATION MEMBER Canon Kabushiki Kaisha (JP) 2013-08-21 EP disclosed
US-8501312-B2 Charging member CANON KABUSHIKI KAISHA (JP) 2013-08-06 US disclosed
US-8491994-B2 Conductive rubber elastic material, charging member and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-07-23 US disclosed
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE HORIKOSHI, HIROYOSHI (CA) 2013-06-27 US disclosed
EP-2581373-A1 BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE Fujita, Takashi (JP) 2013-04-17 EP disclosed
EP-2556051-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS Sumitomo Chemical Company, Limited (JP) 2013-02-13 EP disclosed
US-20120224887-A1 CONDUCTIVE RUBBER ELASTIC MATERIAL, CHARGING MEMBER AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-09-06 US disclosed
CN-102566269-A Color component, color filter and display element JSR K K 2012-07-11 CN disclosed
US-20120141161-A1 CHARGING MEMBER CANON KABUSHIKI KAISHA (JP) 2012-06-07 US disclosed
WO-2011159781-A2 BITTER TASTE MODULATORS SENOMYX, INC. (US) 2011-12-22 WO disclosed
WO-2011126129-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-13 WO disclosed
US-20110105544-A1 CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER CRYSTAX PHARMACEUTICALS, S.L. (ES) 2011-05-05 US disclosed
EP-1263856-A1 STABILIZER COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 2002-12-11 EP disclosed
WO-2001057122-A1 STABILIZER COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 2001-08-09 WO disclosed
US-4460601-A Dipeptides having a methionine residue and possessing a protective action for the liver MAGGIONI FARMACEUTICI, S.P.A. (IT) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105544-A1 CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AKR1C3, TPD52L2, HCCS L3MBTL1 2630/4885POLB 2860/4885ATM 2952/4885
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE PPARG, PPARA, PPARD L3MBTL1 3137/4885POLB 828/4885ATM 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.