Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873176 | 1.00 | EPHX1 (0.70) | EPHX1L3MBTL1POLBATMSMN1; SMN2 | |
| SCHEMBL44800 | 0.85 | L3MBTL1 (0.56) | EPHX1L3MBTL1POLBATMSMN1; SMN2 | |
| SCHEMBL15141726 | 0.83 | L3MBTL1 (0.55) | EPHX1L3MBTL1POLBATMSMN1; SMN2 | |
| SCHEMBL9857113 | 0.81 | POLB (0.54) | EPHX1L3MBTL1POLBATMSMN1; SMN2 | |
| SCHEMBL27633675 | 0.81 | EPHX1 (0.59) | EPHX1 | |
| SCHEMBL7080143 | 0.81 | EPHX1 (0.53) | EPHX1 | |
| SCHEMBL11769885 | 0.80 | PPARG (0.54) | EPHX1L3MBTL1POLBATMSMN1; SMN2 | |
| Propionic Acid SCHEMBL9833196 | 0.79 | POLB (0.51) | EPHX1L3MBTL1POLBATMSMN1; SMN2 | |
| SCHEMBL11204748 | 0.79 | EPHX1 (0.55) | EPHX1L3MBTL1LMNA | |
| SCHEMBL9741104 | 0.79 | L3MBTL1 (0.55) | EPHX1L3MBTL1POLBATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144368-A2 | ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000044709-A2 | ACETYLENIC α-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | claimed |
| EP-1144368-A2 | ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000044709-A2 | ACETYLENIC α-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| US-5719168-A | Acetamide derivatives and their use as feeding behaviour modifiers | LABORATOIRE L. LAFON (FR) | 1998-02-17 | — | — | US | disclosed |