Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3868836 | 0.99 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL3870465 | 0.86 | ACHE (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| Hydrochloric Acid SCHEMBL3866226 | 0.85 | ACHE (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| Hydrochloric Acid SCHEMBL3876242 | 0.85 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL3877268 | 0.83 | ACHE (0.65) | RAB9AACHESLC6A4BCHEGAA | |
| Hydrochloric Acid SCHEMBL3872341 | 0.83 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL3870442 | 0.83 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| Hydrochloric Acid SCHEMBL4002330 | 0.83 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| Hydrochloric Acid SCHEMBL3864622 | 0.82 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| Hydrochloric Acid SCHEMBL3874106 | 0.82 | ACHE (0.64) | RAB9AACHESLC6A4BCHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514475-B2 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-04-07 | — | — | US | claimed |