SCHEMBL4480450

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4481810	0.93	AKT1 (0.44)	AKT1L3MBTL1ALDH1A1CTSLCTSB
	SCHEMBL24716783	0.77	HPGD (0.43)	AKT1NPSR1L3MBTL1HPGDTSHR
	SCHEMBL10565579	0.76	AKT1 (0.49)	AKT1L3MBTL1ALDH1A1CTSLCTSB
	SCHEMBL4085418	0.76	TDP1 (0.51)	AKT1L3MBTL1ALDH1A1CTSLCTSB
	SCHEMBL6440783	0.73	SMN1; SMN2 (0.46)	L3MBTL1HPGDALDH1A1LMNAMEN1
	SCHEMBL277557	0.72	HPGD (0.46)	NPSR1L3MBTL1HPGDTSHRMAPK1
	SCHEMBL7362268	0.71	HPGD (0.44)	NPSR1L3MBTL1HPGDTSHRMAPK1
	SCHEMBL6455153	0.71	ALDH1A1 (0.50)	NPSR1L3MBTL1HPGDTSHRMAPK1
	SCHEMBL3791523	0.71	SMN1; SMN2 (0.47)	NPSR1L3MBTL1HPGDTSHRMAPK1
	SCHEMBL6492852	0.71	NPSR1 (0.47)	NPSR1L3MBTL1HPGDTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.