⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16496273 | 0.64 | — | — | |
| SCHEMBL14919192 | 0.55 | — | — | |
| Ammonia Solution, Strong SCHEMBL13278678 | 0.53 | — | — | |
| SCHEMBL18263253 | 0.50 | — | — | |
| SCHEMBL940795 | 0.50 | — | — | |
| SCHEMBL9564511 | 0.46 | — | — | |
| SCHEMBL1626625 | 0.46 | PRCP (0.45) | — | |
| SCHEMBL213131 | 0.45 | MAPT (0.38) | — | |
| SCHEMBL3618802 | 0.43 | — | — | |
| SCHEMBL17533005 | 0.42 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579343-B2 | Pyrrolo-thiazines and processes for the preparation and use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-08-25 | — | — | US | disclosed |
| EP-1934232-A2 | PYRROLO-THIAZINES AND PROCESSES FOR THE PREPARATION AND USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007030487-A2 | PYRROLO-THIAZINES AND PROCESSES FOR THE PREPARATION AND USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20070055062-A1 | Pyrrolo-thiazines and processes for the preparation and use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-03-08 | — | — | US | disclosed |