Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29883035 | 0.80 | — | — | |
| SCHEMBL29883859 | 0.78 | — | — | |
| SCHEMBL8692424 | 0.78 | MAPT (0.31) | MAPT | |
| SCHEMBL18685897 | 0.76 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL15955539 | 0.72 | — | — | |
| SCHEMBL29199057 | 0.71 | — | — | |
| SCHEMBL3698830 | 0.71 | — | — | |
| SCHEMBL9764579 | 0.69 | — | — | |
| SCHEMBL3618802 | 0.69 | — | — | |
| SCHEMBL12217174 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | claimed |
| US-20220388955-A1 | EP2 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | US | disclosed |
| EP-3992176-A1 | EP2 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210332009-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831810-A1 | BENZENE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10626112-B2 | Heterocyclic sulfonamide derivative and medicine comprising same | EA PHARMA CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-10584116-B2 | Heterocyclic sulfonamide derivative and medicine containing same | EA PHARMA CO., LTD. (JP) | 2020-03-10 | — | — | US | disclosed |
| EP-3101015-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-20070004642-A1 | Oxadiazole derivatives and drugs containing these derivatives as the active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| US-20060287304-A1 | Dihydronaphthalene derivative compounds and agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2006-12-21 | — | — | US | disclosed |
| US-6927286-B1 | Bleomycin gene cluster components and their uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |
| US-20050164954-A1 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2005-07-28 | — | — | US | disclosed |
| US-20050124577-A1 | 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
| US-20050009890-A1 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | ONO PHARMACEUTICAL CO., LTD. | 2005-01-13 | — | — | US | disclosed |
| EP-1082010-A1 | FUNGICIDE MIXTURES BASED ON TRIPLE OXIME ETHER DERIVATIVES AND ADDITIONAL FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000040704-A1 | BLEOMYCIN GENE CLUSTER COMPONENTS AND THEIR USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-07-13 | — | — | WO | disclosed |
| WO-1999048369-A1 | FUNGICIDE MIXTURES BASED ON TRIPLE OXIME ETHER DERIVATIVES AND ADDITIONAL FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-30 | — | — | WO | disclosed |
| US-5412104-A | Hypotensive and antiviral agents | SCHERING CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124577-A1 | 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient | PTGER2, PTGIS, HPGDS | MAPT 2840/4885TDP1 2981/4885SMN1; SMN2 738/4885 |
| US-20050009890-A1 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | CACNA1I, CACNA1B, CACNA1A | MAPT 354/4885TDP1 2479/4885SMN1; SMN2 241/4885 |
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | MAPT 2169/4885TDP1 62/4885SMN1; SMN2 44/4885 |
| US-20220388955-A1 | EP2 ANTAGONIST | PTGER2, PTGER1, PTGES2 | MAPT 3838/4885TDP1 4662/4885SMN1; SMN2 1206/4885 |
| US-20050164954-A1 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ACIN1, CASP7, CASP10 | MAPT 3441/4885TDP1 3986/4885SMN1; SMN2 1845/4885 |
| US-20070004642-A1 | Oxadiazole derivatives and drugs containing these derivatives as the active ingredient | ACIN1, CYCS, CASP7 | MAPT 4639/4885TDP1 2730/4885SMN1; SMN2 2146/4885 |
| US-20060287304-A1 | Dihydronaphthalene derivative compounds and agent comprising the derivative as active ingredient | SREBF1, NR1H2, NR1H3 | MAPT 3348/4885TDP1 3127/4885SMN1; SMN2 4711/4885 |
| US-20210332009-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | MAPT 2169/4885TDP1 62/4885SMN1; SMN2 44/4885 |
| US-10626112-B2 | Heterocyclic sulfonamide derivative and medicine comprising same | TRPA1, TRPV1, TRPV2 | MAPT 1667/4885TDP1 3147/4885SMN1; SMN2 833/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | MAPT 2169/4885TDP1 62/4885SMN1; SMN2 44/4885 |
| US-10584116-B2 | Heterocyclic sulfonamide derivative and medicine containing same | TRPA1, TRPV1, TRPV2 | MAPT 2039/4885TDP1 3036/4885SMN1; SMN2 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.