Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641295 | 1.00 | AKR1B1 (0.51) | AKR1B1AKR1C3AKR1C2PTGER4ALDH1A1 | |
| SCHEMBL8120419 | 1.00 | AKR1B1 (0.51) | AKR1B1AKR1C3AKR1C2PTGER4ALDH1A1 | |
| SCHEMBL27890998 | 0.98 | AKR1B1 (0.50) | AKR1B1AKR1C3AKR1C2PTGER4ALDH1A1 | |
| SCHEMBL599732 | 0.90 | AKR1B1 (0.47) | AKR1B1AKR1C3AKR1C2PTGER4ALDH1A1 | |
| SCHEMBL15695555 | 0.89 | ALDH1A1 (0.48) | AKR1B1AKR1C3AKR1C2PTGER4ALDH1A1 | |
| SCHEMBL28241058 | 0.89 | ALDH1A1 (0.48) | AKR1B1AKR1C3AKR1C2PTGER4ALDH1A1 | |
| SCHEMBL17782926 | 0.86 | ALDH1A1 (0.50) | PTGER4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11691644 | 0.85 | AKR1B1 (0.65) | AKR1B1AKR1C3AKR1C2PTGER4CXCL8 | |
| SCHEMBL3315435 | 0.85 | PTGER4 (0.47) | PTGER4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL1566758 | 0.85 | ALDH1A1 (0.48) | AKR1B1PTGER4ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365556-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | claimed |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | claimed |
| CN-113862058-B | Lubricating oil composition and preparation method thereof | 中国石油化工股份有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114502152-A | Pharmaceutical composition for topical use in the form of a dispersed phase based on at least one short-chain diol and comprising at least one anti-inflammatory substance in a continuous fatty phase | 化工产品开发公司SEPPIC | 2022-05-13 | — | — | CN | claimed |
| CN-113861032-A | Ester compound, preparation method and application thereof, and lubricating oil composition | 中国石油化工股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113861031-A | Ester compound, preparation method and application thereof, and lubricating oil composition | 中国石油化工股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113862058-A | Lubricating oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-112739326-A | Pharmaceutical composition for topical use comprising at least one anti-inflammatory substance | 化工产品开发公司SEPPIC | 2021-04-30 | — | — | CN | claimed |
| CN-109456201-B | Method for asymmetrically synthesizing (R) -cinacalcet | 中国农业大学 | 2020-04-28 | — | — | CN | claimed |
| US-10604520-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2020-03-31 | — | — | US | claimed |
| EP-0143371-B1 | PROCESS FOR THE OPTICAL RESOLUTION OF RACEMIC MIXTURES OF ALPHA-NAPHTHYL-PROPIONIC ACIDS | ALFA CHEM ITAL (IT) | 1988-02-24 | — | — | EP | claimed |
| US-4724102-A | Optical resolution of racemic mixtures of alpha-naphthylpropionic acids and derivatives of said acids | ALFA CHEMICALS ITALIANA S.P.A. (IT) | 1988-02-09 | — | — | US | claimed |
| US-4723033-A | REACTING ALPHA METAL ACID DERIVATIVE AND ARYL HALIDE WITH OPTICALLY ACTIVE CATALYST | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1988-02-02 | — | — | US | claimed |
| EP-0220805-A2 | Multiphase tablet and process for the preparation thereof | Euroceltique S.A. (LU) | 1987-05-06 | — | — | EP | claimed |
| US-4661628-A | Process for the optical resolution of racemic mixtures of α-naphthyl-propionic acids | ALFA CHEMICALS ITALIANA S.P.A. (IT) | 1987-04-28 | — | — | US | claimed |
| EP-0204911-A2 | A new process for the optical resolution of racemic mixtures of alpha-naphthylpropionic acids | ALFA WASSERMANN S.p.A. (IT) | 1986-12-17 | — | — | EP | claimed |
| US-4622419-A | AMIDATION, ACID HYDROLYSIS | ALFA CHEMICALS ITALIANA S.P.A. (IT) | 1986-11-11 | — | — | US | claimed |
| EP-0143371-A1 | Process for the optical resolution of racemic mixtures of alpha-naphthyl-propionic acids | Alfa Chemicals Italiana S.r.l. (IT) | 1985-06-05 | — | — | EP | claimed |
| US-4187196-A | REACTING HALOGENATED TITANIUM COMPOUND WITH MAGNESIUM OR MANGANESE DIHALIDE | MONTEDISON S.P.A. (IT) | 1980-02-05 | — | — | US | claimed |
| US-4107414-A | Process for the stereoregular polymerization of alpha olefins | MONTECATINI EDISON S.P.A. (IT) | 1978-08-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604520-B2 | N-acyl amino acid compounds and methods of use | ITGA1, ITGB1, ITGAL | AKR1B1 1940/4885AKR1C3 2024/4885AKR1C2 2477/4885 |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | ITGA1, ITGB1, ITGAL | AKR1B1 1940/4885AKR1C3 2024/4885AKR1C2 2477/4885 |
| US-20230365556-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | ITGA1, ITGB1, ITGAL | AKR1B1 1940/4885AKR1C3 2024/4885AKR1C2 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.