Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244589 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LAP3KYNUSLC15A1SLC1A3 | |
| SCHEMBL28012939 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL10762480 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LAP3KYNUKMT2AELANE | |
| SCHEMBL27656879 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL27591574 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL14793800 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LAP3KYNUKMT2AELANE | |
| SCHEMBL7669860 | 0.77 | SLC1A1 (0.58) | ALDH1A1LAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL27628195 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL9110890 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LAP3SLC15A1SLC1A3SLC1A1 | |
| SCHEMBL11170311 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LAP3KYNUSLC15A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598241-B2 | 2-[3-(4-chlorophenyl)ureido] N-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-4-methanesulfonylbutyramide; prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors | MERCK PATENT GMBH (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20060074072-A1 | Carboxamide derivatives and their use as factor xa inhibitors | MERCK PATENT GMBH (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074072-A1 | Carboxamide derivatives and their use as factor xa inhibitors | F11, F12, F10 | ALDH1A1 2219/4885LAP3 2696/4885KYNU 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.