Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94149 | 0.65 | GSK3B (0.58) | PTGS2PDE4BGSK3B | |
| SCHEMBL114611 | 0.65 | PTGS2 (0.67) | PTGS2PDE4BGSK3B | |
| SCHEMBL3815134 | 0.64 | PTGS2 (0.65) | PTGS2GSK3BPOLBHPGDHSD17B10 | |
| SCHEMBL7645920 | 0.63 | KMT2A (0.43) | PTGS2PDE4BGSK3BALDH1A1PARP10 | |
| SCHEMBL20161110 | 0.63 | PDE4B (0.54) | PTGS2PDE4BALDH1A1MAPTMITF | |
| SCHEMBL7258464 | 0.63 | PDE4B (0.54) | PTGS2PDE4BALDH1A1MAPTMITF | |
| SCHEMBL28257026 | 0.63 | PDE4B (0.54) | PTGS2PDE4BALDH1A1MAPTMITF | |
| SCHEMBL9474080 | 0.63 | PTGS2 (0.64) | PTGS2GSK3B | |
| SCHEMBL20121190 | 0.63 | PDE4B (0.54) | PTGS2PDE4BALDH1A1MAPTMITF | |
| SCHEMBL8783438 | 0.63 | CLK4 (0.43) | PTGS2PDE4BGSK3BPARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054033-A2 | LIQUID PREPARATION | Asubio Pharma Co., Ltd. (JP) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008016165-A2 | LIQUID PREPARATION | ASUBIO PHARMA CO., LTD. (JP) | 2008-02-07 | — | — | WO | disclosed |