⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709145 | 0.65 | — | — | |
| SCHEMBL47206 | 0.65 | — | — | |
| SCHEMBL2008205 | 0.62 | — | — | |
| SCHEMBL682505 | 0.59 | — | — | |
| SCHEMBL10768177 | 0.59 | PKM (0.78) | — | |
| SCHEMBL272744 | 0.57 | — | — | |
| SCHEMBL7442697 | 0.57 | — | — | |
| SCHEMBL18483391 | 0.57 | — | — | |
| SCHEMBL193967 | 0.57 | — | — | |
| SCHEMBL14042394 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010938-A | Pyrido [1, 2-a ] pyrimidine mesoionic derivative containing five-membered heterocyclic structure, and preparation and application thereof | 贵州大学 | 2026-05-12 | — | — | CN | disclosed |
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20250129070-A1 | BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS | KOLM THERAPEUTICS INC. | 2025-04-24 | — | — | US | disclosed |
| WO-2025081082-A1 | BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS | KOLM THERAPEUTICS INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| WO-2025036241-A1 | COMPOUNDS AND METHODS FOR MODULATING RNA SPLICING | RIBOPEUTIC INC. (CN) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024211663-A1 | CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-10-10 | — | — | WO | disclosed |
| CN-116731038-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2021130515-A1 | STRUCTURALLY SIMPLIFIED DIAZONAMIDE ANALOGS AS ANTIMITOTIC AGENTS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2021-07-01 | — | — | WO | disclosed |
| CN-112409378-A | Tricyclic PI3K inhibitor compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-1501808-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091227-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-06 | — | — | WO | disclosed |
| US-5958973-A | Polyhydroxy benzoic acid derivatives and their use as neuraminidase inhibitors | GILEAD SCIENCES, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5512596-A | Aromatic compounds | GILEAD SCIENCES, INC. (US) | 1996-04-30 | — | — | US | disclosed |
| CN-1082043-A | Be applicable to that the preparation antithrombotic forms and the compound 7-oxabicyclo heptyl of vasospasm replaces De oxazole amide prostaglandin analog intermediates preparation | SQUIBB & SONS INC (US) | 1994-02-16 | — | — | CN | disclosed |
| US-5283363-A | Reacting a halogeno(hetero)aryl compound with aminoalkynyl compounds; catalysts; hydrogenation | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| US-5281716-A | Enzyme inhibitors for anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0575069-A1 | Method for preparing 7-oxabicycloheptyl substituted oxazole amide prostaglandin analog intermediates useful in the preparation of antithrombotic and anti-vasospastic compounds | E.R. Squibb & Sons, Inc. (US) | 1993-12-22 | — | — | EP | disclosed |
| EP-0497133-A1 | Process for the preparation of (hetero)arylalk(en/in)-ylamines and (hetero)arylalkinylamines per se | BAYER AG (DE) | 1992-08-05 | — | — | EP | disclosed |
| US-4180670-A | Amino pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-12-25 | — | — | US | disclosed |