SCHEMBL4482770

SCHEMBL4482770

CC(C)CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
KMT2A Q03164 5/20 0.51
MEN1 O00255 3/20 0.51
GAA P10253 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ELANE P08246 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
RAB9A P51151 3/20 0.49
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49
CASP3 P42574 2/20 0.48
CA12 O43570 1/20 0.48
CA9 Q16790 1/20 0.48
GLS O94925 1/20 0.48
NPC1 O15118 2/20 0.48
DRD3 P35462 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30377710 1.00 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1GAAL3MBTL1
Sulfuric Acid SCHEMBL29217908 0.91 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1GAAL3MBTL1
SCHEMBL9340887 0.87 ALDH1A1 (0.53) ALDH1A1KMT2AELANERAB9AHPGD
SCHEMBL14928576 0.84 ELANE (0.53) ALDH1A1KMT2AMEN1GAAL3MBTL1
SCHEMBL10210078 0.84 ELANE (0.53) ALDH1A1KMT2AMEN1GAAL3MBTL1
SCHEMBL14928830 0.83 ALDH1A1 (0.50) ALDH1A1KMT2AELANENPSR1CASP3
SCHEMBL19301893 0.83 ALDH1A1 (0.50) ALDH1A1KMT2AELANECASP3CA12
SCHEMBL3379010 0.83 ELANE (0.51) ALDH1A1KMT2AELANERAB9AHPGD
SCHEMBL17280822 0.83 ALDH1A1 (0.64) ALDH1A1KMT2AELANERAB9ACA12
SCHEMBL4681409 0.83 ALDH1A1 (0.52) ALDH1A1KMT2AELANERAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349678-B Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2024-04-26 CN claimed
CN-114349678-A Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2022-04-15 CN claimed
CN-109944097-B Yilun printed fabric and printing method thereof 广东溢达纺织有限公司 2021-05-14 CN claimed
CN-109944097-A Instrument synthetic fibre PRINTED FABRIC and its printing method 广东溢达纺织有限公司 2019-06-28 CN claimed
CN-109206355-A It is the method that one step of starting material constructs N- isobutylphthalimide using imines 桂林理工大学 2019-01-15 CN claimed
EP-0286995-B1 A COMPOSITION FOR DYEING MATERIAL OF SYNTHETIC AROMATIC POLYAMIDE FIBRES Chemische Fabrik Stockhausen GmbH (DE) 1993-03-10 EP claimed
US-4780105-A EMULSIFIERS, SURFACTANTS; ODORLESS STOCKHAUSEN, INC. (US) 1988-10-25 US claimed
EP-0286995-A2 A composition for dyeing material of synthetic aromatic polyamide fibres Chemische Fabrik Stockhausen GmbH (DE) 1988-10-19 EP claimed
CN-114349678-B Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2024-04-26 CN disclosed
CN-116903517-A Preparation method of 4-nitro-N-alkylphthalimide 广东优巨先进新材料股份有限公司 2023-10-20 CN disclosed
EP-3744723-B1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND SHENZHEN TARGETRX INC (CN) 2023-10-18 EP disclosed
WO-2023196556-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CORBUS PHARMACEUTICALS, INC. (US) 2023-10-12 WO disclosed
WO-2023180976-A1 INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS FOR USING SAME 1ST Biotherapeutics, Inc. (KR) 2023-09-28 WO disclosed
US-20230286970-A1 NOVEL OXADIAZOLE-BASED SELECTIVE HDAC6 INHIBITORS ITALFARMACO SPA (IT) 2023-09-14 US disclosed
EP-0286995-B1 A COMPOSITION FOR DYEING MATERIAL OF SYNTHETIC AROMATIC POLYAMIDE FIBRES Chemische Fabrik Stockhausen GmbH (DE) 1993-03-10 EP disclosed
EP-0514667-A1 Benzazepin derivatives as vasopressin antagonists OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-25 EP disclosed
EP-0450097-A1 BENZOHETEROCYCLIC COMPOUNDS. OTSUKA PHARMA CO LTD (JP) 1991-10-09 EP disclosed
WO-1991005549-A1 BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-05-02 WO disclosed
US-4780105-A EMULSIFIERS, SURFACTANTS; ODORLESS STOCKHAUSEN, INC. (US) 1988-10-25 US disclosed
EP-0286995-A2 A composition for dyeing material of synthetic aromatic polyamide fibres Chemische Fabrik Stockhausen GmbH (DE) 1988-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286970-A1 NOVEL OXADIAZOLE-BASED SELECTIVE HDAC6 INHIBITORS HDAC6, HDAC1, HDAC3 ALDH1A1 980/4885KMT2A 73/4885MEN1 4567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.