SCHEMBL4482805

SCHEMBL4482805

CCO/C=C/C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2982580 1.00
SCHEMBL6109145 0.84 CASP1 (0.30)
Butane SCHEMBL9123038 0.81 LMNA (0.46)
SCHEMBL7831010 0.74
SCHEMBL11496418 0.74
SCHEMBL1407387 0.73
SCHEMBL8052611 0.73
SCHEMBL1407388 0.73
SCHEMBL9681822 0.73
SCHEMBL9681826 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0380392-B1 Derivatives of benzocycloalkenyl dihydroxyalkanoic acids, methods of making them and phrmaceuticals containing them LIPHA (FR) 1994-04-20 EP claimed
CN-108264450-B Preparation method of polysubstituted phenol 浙江省诸暨合力化学对外贸易有限公司 2021-04-30 CN disclosed
CN-111269187-A Environment-friendly synthesis method of sulfadiazine 湖南吴赣药业有限公司 2020-06-12 CN disclosed
EP-1538145-B1 PROCESS FOR PRODUCTION OF PHENOXY-SUBSTITUTED 2-PYRIDONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2016-02-17 EP disclosed
US-8071770-B2 Spirohydantoin aryl CGRP receptor antagonists MERCK SHARP & DOHME CORP. (US) 2011-12-06 US disclosed
US-8071772-B2 Spirolactam bicyclic CGRP receptor antagonists MERCK SHARP & DOHME CORP. (US) 2011-12-06 US disclosed
US-7851464-B2 Spirolactam aryl CGRP receptor antagonists MERCK SHARP & DOHME CORP. (US) 2010-12-14 US disclosed
US-7790734-B2 Dipeptidyl peptidase inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-09-07 US disclosed
US-20100016603-A1 PRODUCTION PROCESS OF 2,3'-BIPYRIDYL-6'-ONE FUJIFILM FINECHEMICALS CO., LTD. (JP) 2010-01-21 US disclosed
US-20100016603-A1 PRODUCTION PROCESS OF 2,3'-BIPYRIDYL-6'-ONE FUJIFILM FINECHEMICALS CO., LTD. (JP) 2010-01-21 US disclosed
US-20050250713-A1 11,12-Cyclic thiocarbamate macrolide antibacterial agents ZHU BIN 2005-11-10 US disclosed
US-20050154210-A1 Process for production of phenoxy-substituted 2-pyridone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 US disclosed
EP-1538145-A1 PROCESS FOR PRODUCTION OF PHENOXY-SUBSTITUTED 2-PYRIDONE COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed
EP-0387032-B1 TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME CHISSO CORP (JP) 1993-06-16 EP disclosed
US-5183924-A Anticholesterol agents, antithrombotics, fungicides LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1993-02-02 US disclosed
US-5082859-A Anticholesterol, anticoagulant, fungicide LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1992-01-21 US disclosed
EP-0257557-B1 PROCESS FOR THE PREPARATION OF BIFUNCTIONAL COMPOUNDS BASF Aktiengesellschaft (DE) 1991-12-04 EP disclosed
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed
EP-0387032-A1 Trifluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1990-09-12 EP disclosed
US-4321387-A Process for the preparation of optically active nicotine analogs PHILIP MORRIS, INCORPORATED (US) 1982-03-23 US disclosed