Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.47 |
| ▸ | TLR2 | O60603 | 8/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481628 | 0.89 | CETP (0.49) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL8735923 | 0.87 | CETP (0.48) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL7813151 | 0.85 | LPAR1 (0.52) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL25335565 | 0.85 | LPAR1 (0.67) | CETPLPAR1LPAR3LPAR2 | |
| SCHEMBL385051 | 0.85 | LPAR1 (0.67) | CETPLPAR1LPAR3LPAR2 | |
| SCHEMBL31069863 | 0.85 | LPAR1 (0.67) | CETPLPAR1LPAR3LPAR2 | |
| SCHEMBL10605748 | 0.84 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL10604578 | 0.84 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL10604671 | 0.84 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL18641859 | 0.84 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | claimed |
| US-7517858-B1 | Prodrugs of pharmaceuticals with improved bioavailability | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-14 | — | — | US | disclosed |
| EP-0837630-B1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | HOSTETLER KARL Y (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6002029-A | Antiviral prodrugs | CHIMERIX, INC. | 1999-12-14 | — | — | US | disclosed |
| EP-0837630-A4 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | UNIV CALIFORNIA (US) | 1998-11-25 | — | — | EP | disclosed |
| EP-0837630-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0792275-A4 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 1998-02-25 | — | — | EP | disclosed |
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0792275-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996039831-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996015132-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-23 | — | — | WO | disclosed |