Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483073 | 0.87 | CETP (0.50) | CETPLPAR1LPAR3TLR2ALDH1A1 | |
| SCHEMBL10519397 | 0.83 | TLR2 (0.45) | TLR2ALDH1A1LMNA | |
| SCHEMBL4481628 | 0.83 | CETP (0.49) | CETPLPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL31069863 | 0.83 | LPAR1 (0.67) | CETPLPAR1LPAR3LPAR2 | |
| SCHEMBL385051 | 0.83 | LPAR1 (0.67) | CETPLPAR1LPAR3LPAR2 | |
| SCHEMBL9575700 | 0.83 | TLR2 (0.44) | TLR2ALDH1A1LMNA | |
| SCHEMBL10604671 | 0.82 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2TDP1 | |
| SCHEMBL10605748 | 0.82 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2TDP1 | |
| SCHEMBL10604578 | 0.82 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2TDP1 | |
| SCHEMBL18641859 | 0.82 | PLA2G10 (0.47) | CETPLPAR1LPAR3TLR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | claimed |
| EP-0792275-A4 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0792275-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015132-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-23 | — | — | WO | disclosed |