Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453256 | 0.84 | HTR2A (0.43) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL10853706 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1HTR2AAOC3 | |
| SCHEMBL7956561 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL7960344 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL7956563 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL7763313 | 0.79 | TDP1 (0.42) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL28046650 | 0.79 | KDM4E (0.42) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL16103787 | 0.77 | LMNA (0.50) | LMNAKDM4EALDH1A1HTR2AAOC3 | |
| SCHEMBL15214945 | 0.77 | LMNA (0.50) | LMNAKDM4EALDH1A1HTR2AAOC3 | |
| SCHEMBL4594703 | 0.77 | LMNA (0.50) | LMNAKDM4EALDH1A1HTR2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094292-A2 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | Ikor, Inc. (US) | 2009-09-02 | — | — | EP | claimed |
| WO-2008051689-A2 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR, INC. (US) | 2008-05-02 | — | — | WO | claimed |