Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | GSK3A | P49840 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500115 | 0.88 | GSK3B (0.66) | GSK3BCYP1A2CDK2GSK3A | |
| SCHEMBL4487628 | 0.86 | GSK3B (0.72) | GSK3BCYP1A2CDK2GSK3A | |
| SCHEMBL4492040 | 0.86 | GSK3B (0.68) | GSK3BCYP1A2CDK2GSK3A | |
| SCHEMBL1461524 | 0.83 | GSK3B (0.67) | GSK3BCYP1A2 | |
| SCHEMBL4479151 | 0.83 | GSK3B (0.68) | GSK3BCYP1A2CDK2GSK3A | |
| SCHEMBL31060453 | 0.82 | GSK3B (1.00) | GSK3BCYP1A2GSK3A | |
| SCHEMBL4493121 | 0.82 | GSK3B (1.00) | GSK3BCYP1A2GSK3A | |
| SCHEMBL1460286 | 0.81 | GSK3B (1.00) | GSK3BCYP1A2 | |
| SCHEMBL31061533 | 0.81 | GSK3B (1.00) | GSK3BCYP1A2 | |
| SCHEMBL4494906 | 0.81 | GSK3B (0.60) | GSK3BCYP1A2CDK2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632854-B2 | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PFIZER ITALIA S.R.L. (IT) | 2009-12-15 | — | — | US | claimed |