Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477332 | 0.87 | NR3C1 (0.36) | NR3C1PGRNR3C2ARESR1 | |
| SCHEMBL4513404 | 0.85 | NR3C1 (0.39) | NR3C1PGRNR3C2ARESR1 | |
| SCHEMBL4487265 | 0.83 | NR3C1 (0.41) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120806 | 0.82 | NR3C1 (0.40) | NR3C1PGRNR3C2AR | |
| SCHEMBL4486735 | 0.82 | NR3C1 (0.40) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120837 | 0.81 | NR3C1 (0.38) | NR3C1PGRNR3C2AR | |
| SCHEMBL4484189 | 0.77 | ADRB3 (0.55) | DRD2DRD3 | |
| SCHEMBL1120802 | 0.74 | NR3C1 (0.38) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120907 | 0.73 | ESR1 (0.41) | NR3C1ESR1ESR2 | |
| SCHEMBL1120793 | 0.72 | NR3C1 (0.39) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511069-B2 | Indazole compounds as β3 andrenoceptor agonist | ASAHI PHARMA CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |