Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120806 | 0.85 | NR3C1 (0.40) | NR3C1PGRNR3C2AR | |
| SCHEMBL4484186 | 0.84 | NR3C1 (0.42) | NR3C1PGRNR3C2ARACHE | |
| SCHEMBL4635188 | 0.83 | NR3C1 (0.40) | NR3C1PGRNR3C2ARACHE | |
| SCHEMBL1120837 | 0.82 | NR3C1 (0.38) | NR3C1PGRNR3C2AR | |
| SCHEMBL4484871 | 0.82 | KDM4E (0.44) | NR3C1PGRNR3C2ARACHE | |
| SCHEMBL4484191 | 0.82 | NR3C1 (0.37) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120802 | 0.76 | NR3C1 (0.38) | NR3C1PGRNR3C2AR | |
| SCHEMBL4486734 | 0.75 | ADRB3 (0.59) | — | |
| SCHEMBL1120796 | 0.75 | NR3C1 (0.43) | NR3C1PGRNR3C2AR | |
| SCHEMBL1120828 | 0.75 | NR3C1 (0.41) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511069-B2 | Indazole compounds as β3 andrenoceptor agonist | ASAHI PHARMA CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |