SCHEMBL448455

SCHEMBL448455

CCCC(CC)OC(=O)C=CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.52
PRKCA P17252 2/20 0.41
PRKCD Q05655 2/20 0.41
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
CTSK P43235 2/20 0.35
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ATM Q13315 1/20 0.34
TSHR P16473 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100840 1.00 HCAR2 (0.52) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL2099662 1.00 HCAR2 (0.52) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL2099660 0.92 PRKCA (0.45) HCAR2PRKCAPRKCDCTSKCHRM1
SCHEMBL2100839 0.92 PRKCA (0.45) HCAR2PRKCAPRKCDCTSKCHRM1
SCHEMBL29288086 0.91 HCAR2 (0.53) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL20563819 0.89 ACHE (0.44) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL308468 0.89 HCAR2 (0.54) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL952463 0.89 HCAR2 (0.54) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL2896249 0.89 HCAR2 (0.54) HCAR2PRKCAPRKCDACHEBACE1
SCHEMBL5175099 0.88 HCAR2 (0.59) HCAR2CTSKTDP1ATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107699215-A Preparation method of polyamide inhibitor for drilling fluid 中国石油集团川庆钻探工程有限公司 2018-02-16 CN claimed
CN-105085805-A Polystyrene dipropyl butenedioate as well as preparation method and application thereof PETROCHINA CO LTD 2015-11-25 CN claimed
CN-101780381-B N-alkylasparagine surfactant and preparation method thereof DAQING ZHUOYUE CHEMICAL TECHNOLOGY CO., LTD. (CN) 2011-12-28 CN claimed
CN-101780381-A N-alkylasparagine surfactant and preparation method thereof DAQING ZHUOYUE CHEMICAL TECHNO 2010-07-21 CN claimed
WO-2010019647-A2 FABRICATING FIBERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-02-18 WO claimed
US-20100041804-A1 FABRICATING FIBERS DOW EUROPE GMBH (CH) 2010-02-18 US claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP disclosed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP disclosed
EP-4584243-B1 CROSSLINKERS HEMOTEQ AG (DE) 2025-11-05 EP disclosed
EP-4584244-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584243-A1 CROSSLINKERS Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584245-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
EP-0243605-B1 FLUORINE-CONTAINING RESIN COMPOSITION HAVING A LOW REFRACTIVE INDEX DAINIPPON INK AND CHEMICALS, INC. (JP) 1993-06-16 EP disclosed
CN-1014235-B Process for production of dialkyl maleate DAVY MCKEE LTD (GB) 1991-10-09 CN disclosed
US-4884866-A OPTICAL FIBERS DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-12-05 US disclosed
US-4800216-A ACRYLONITRILE-BUTADIENE-STYRENE BAYER AKTIENGESELLSCHAFT (DE) 1989-01-24 US disclosed
US-4786658-A ACRYLIC ESTER POLYMER, CLADDING FOR OPTICAL FIBERS DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-11-22 US disclosed
CN-87105385-A Technological process 1988-04-27 CN disclosed
EP-0243605-A2 Fluorine-containing resin composition having a low refractive index DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-11-04 EP disclosed