SCHEMBL448493

SCHEMBL448493

C[Si](C)(C)O[Si](CCN)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL303927 0.83 ODC1 (0.33)
SCHEMBL449036 0.81 NFKB1 (0.35)
SCHEMBL10753254 0.81 ODC1 (0.32)
SCHEMBL3617414 0.81
SCHEMBL446941 0.79 DNM1 (0.38)
SCHEMBL10753439 0.79 NFKB1 (0.33)
SCHEMBL449385 0.79 DNM1 (0.38)
SCHEMBL446507 0.79 DNM1 (0.38)
SCHEMBL9221215 0.77
SCHEMBL8679000 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011889-B1 PRIMARY AMINOSILOXANE COMPOUND AND METHOD FOR PRODUCING SAME SHINETSU CHEMICAL CO (JP) 2025-09-03 EP disclosed
EP-2307190-B1 SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS NOVARTIS AG (CH) 2015-03-18 EP disclosed
US-8883928-B2 Silicone-containing polymeric materials with hydrolyzable groups NOVARTIS AG (CH) 2014-11-11 US disclosed
US-20120065331-A1 SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS ALCON INC. (CH) 2012-03-15 US disclosed
US-8079703-B2 Silicone-containing polymeric materials with hydrolyzable groups NOVARTIS AG (CH) 2011-12-20 US disclosed
EP-2307190-A1 SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS Novartis AG (CH) 2011-04-13 EP disclosed
WO-2010011493-A1 SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS NOVARTIS AG (CH) 2010-01-28 WO disclosed
US-20100014047-A1 Silicone-Containing Polymeric Materials with Hydrolyzable Groups ALCON INC. (CH) 2010-01-21 US disclosed
EP-0648796-B1 Solutions of polyimide-forming substances and their use SCHENECTADY INT INC (US) 1998-08-26 EP disclosed
US-5493003-A MIXTURES OF AMINES, AMIDES AND/OR ESTERS OF TETRACARBOXYLIC ACIDS HAVING AMIDO OR ESTER GROUPS SUBSTITUTED WITH CARBOXYL, SULFO, SILYL OR SILOXY GROUPS, ELECTRONICS BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
EP-0648796-A1 Solutions of polyimide-forming substances and their use BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
US-4038293-A Silicone-compatible tris(trimethylsilyloxy)silylalkylamino-substituted quinoncid dyestuffs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-26 US disclosed
US-3981859-A Silicone-compatible azo dyestuffs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-09-21 US disclosed
US-3963744-A Silicone-compatible phthalocyanine dyestuffs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-06-15 US disclosed