Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346053 | 0.86 | NPSR1 (0.55) | LMNAALDH1A1NPSR1KDM4EMAPK1 | |
| SCHEMBL4185865 | 0.80 | KMT2A (0.48) | LMNAALDH1A1NPSR1KDM4E | |
| SCHEMBL4566093 | 0.78 | NPC1 (0.49) | LMNAALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL4188335 | 0.75 | ALDH1A1 (0.46) | LMNAALDH1A1NPSR1KDM4EMAPK1 | |
| SCHEMBL4338832 | 0.72 | KDM4E (0.61) | ALDH1A1KDM4EMAPK1SMN1; SMN2HPGD | |
| SCHEMBL4346565 | 0.71 | ALDH1A1 (0.67) | LMNAALDH1A1NPSR1KDM4ETSHR | |
| SCHEMBL2990484 | 0.68 | HDAC3 (0.65) | LMNAALDH1A1MAPK1 | |
| SCHEMBL3679343 | 0.67 | MEN1 (0.55) | LMNAALDH1A1NPSR1KDM4ETSHR | |
| SCHEMBL4797746 | 0.66 | KMT2A (0.73) | ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL4784357 | 0.64 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | disclosed |