Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180223 | 0.88 | ALDH1A1 (0.44) | KMT2AKDM4EMEN1LMNAALDH1A1 | |
| SCHEMBL4196907 | 0.84 | ALDH1A1 (0.57) | KMT2AKDM4EMEN1LMNAALDH1A1 | |
| SCHEMBL4346053 | 0.81 | NPSR1 (0.55) | KDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL4484979 | 0.80 | LMNA (0.45) | KDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL4178799 | 0.80 | NPSR1 (0.47) | KMT2AKDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4189591 | 0.76 | MEN1 (0.43) | KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL4194030 | 0.75 | LMNA (0.55) | KMT2AKDM4EMEN1LMNAALDH1A1 | |
| SCHEMBL4190437 | 0.74 | LMNA (0.61) | KMT2AKDM4EMEN1LMNAALDH1A1 | |
| SCHEMBL4566093 | 0.73 | NPC1 (0.49) | KMT2AMEN1LMNAALDH1A1NPSR1 | |
| SCHEMBL4732905 | 0.72 | L3MBTL1 (0.81) | KMT2AKDM4EMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | disclosed |