Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379080 | 0.72 | MAPK14 (0.52) | — | |
| SCHEMBL7249926 | 0.71 | MRGPRX4 (0.49) | PTPN1IDO1MAOBMAOASLC6A4 | |
| SCHEMBL4489354 | 0.71 | MAPK14 (0.70) | PTPN1IDO1MAOBFFAR1FFAR4 | |
| SCHEMBL4381782 | 0.71 | MAPK14 (0.49) | PTPN1MAOBMAOASLC6A4FFAR1 | |
| SCHEMBL27299287 | 0.69 | HSD17B10 (0.41) | DAO | |
| SCHEMBL10391261 | 0.69 | TAS2R14 (0.47) | PTPN1MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL13154275 | 0.68 | FFAR1 (0.57) | IDO1MAOBMAOASLC6A4FFAR1 | |
| SCHEMBL2292699 | 0.68 | IDO1 (0.54) | PTPN1IDO1MAOBMAOASLC6A4 | |
| SCHEMBL29452503 | 0.68 | ALDH1A1 (0.54) | PTPN1IDO1MAOBMAOASLC6A4 | |
| SCHEMBL29629421 | 0.67 | ALDH1A1 (0.62) | IDO1MAOBMAOAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |