Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | BACE1 | P56817 | 6/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485008 | 0.88 | P2RX7 (0.45) | BCHEACHEBACE1CD274PDCD1LG2 | |
| SCHEMBL5437369 | 0.86 | SIGMAR1 (0.44) | BCHEACHEBACE1CD274PDCD1LG2 | |
| SCHEMBL4687118 | 0.85 | SCN9A (0.47) | L3MBTL1 | |
| SCHEMBL6112140 | 0.85 | SCN9A (0.47) | L3MBTL1 | |
| SCHEMBL18919696 | 0.78 | BCHE (0.46) | BCHEACHEBACE1TEAD1LTA4H | |
| SCHEMBL18919693 | 0.78 | BCHE (0.46) | BCHEACHEBACE1TEAD1LTA4H | |
| SCHEMBL696022 | 0.77 | GLA (0.45) | BCHEACHEBACE1CD274POLB | |
| SCHEMBL5505247 | 0.77 | SLC6A2 (0.52) | BCHEACHEBACE1TEAD1LTA4H | |
| SCHEMBL4477584 | 0.76 | BCHE (0.58) | BCHEACHEBACE1EPHX2SIGMAR1 | |
| SCHEMBL5508297 | 0.75 | BCHE (0.42) | BCHEACHEBACE1TEAD1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619096-B2 | 3-Aminopyrrolidines as inhibitors of monoamine uptake | ELI LILLY AND COMPANY (US) | 2009-11-17 | — | — | US | disclosed |