Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541807 | 0.91 | KMT2A (0.70) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL23531478 | 0.91 | KMT2A (0.70) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL28130536 | 0.91 | KMT2A (0.70) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL25376808 | 0.86 | KMT2A (0.64) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL29238442 | 0.82 | KMT2A (0.58) | KMT2AL3MBTL1ATMPKM | |
| SCHEMBL14690575 | 0.82 | KMT2A (0.58) | KMT2AL3MBTL1ATMPKM | |
| SCHEMBL17850457 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL3196036 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL2237397 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1L3MBTL1ATMPKM | |
| SCHEMBL10288644 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1L3MBTL1ATMPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615651-B2 | Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof | PFIZER INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-20080167371-A1 | Diaryl, Dipyridinyl and Aryl-Pyridinyl Derivatives and Uses Thereof | PFIZER INC. | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167371-A1 | Diaryl, Dipyridinyl and Aryl-Pyridinyl Derivatives and Uses Thereof | OPRD1, OPRK1, OPRL1 | KMT2A 1765/4885ALDH1A1 1390/4885L3MBTL1 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.