SCHEMBL4486308

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4497855	0.92	PTGDR (0.51)	CSNK2A2CSNK2A1ALDH1A1ACP1GPBAR1
	SCHEMBL4488036	0.91	TACR3 (0.51)	CSNK2A2CSNK2A1ACP1GPBAR1PTGDR
	SCHEMBL4478359	0.89	PTGDR (0.46)	CSNK2A2CSNK2A1ALDH1A1GPBAR1PTGDR
	SCHEMBL4484812	0.88	PTGDR (0.46)	CSNK2A2CSNK2A1ALDH1A1GPBAR1PTGDR
	SCHEMBL4484055	0.88	CSNK2A2 (0.52)	CSNK2A2CSNK2A1ALDH1A1ACP1GPBAR1
	SCHEMBL4487805	0.87	NFKB1 (0.48)	CSNK2A2CSNK2A1ACP1GPBAR1PTGDR
	SCHEMBL4492686	0.87	CSNK2A2 (0.55)	CSNK2A2CSNK2A1ALDH1A1MEN1KMT2A
	SCHEMBL4493553	0.85	KMT2A (0.57)	ALDH1A1MEN1KMT2AMAPTCYP3A4
	SCHEMBL4488271	0.85	MAPT (0.50)	ALDH1A1PTGDRMEN1KMT2AMAPT
	SCHEMBL4490373	0.85	CA1 (0.55)	ALDH1A1KMT2AMAPTTP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.