SCHEMBL448685

SCHEMBL448685

C=CC(=O)OCCOC(=O)C=CC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.61
ALDH1A1 P00352 4/20 0.61
TP53 P04637 4/20 0.61
HIF1A Q16665 3/20 0.61
HSD17B10 Q99714 1/20 0.61
HCAR2 Q8TDS4 8/20 0.61
CYP3A4 P08684 2/20 0.56
THRB P10828 2/20 0.50
HPGD P15428 1/20 0.50
ATM Q13315 1/20 0.43
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448684 1.00 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8892905 1.00 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
Maleic Acid SCHEMBL3892059 0.96 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL447514 0.92 TSHR (0.69) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8893359 0.92 TSHR (0.69) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5393810 0.92 HCAR2 (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5393799 0.92 HCAR2 (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL447515 0.92 TSHR (0.69) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9159451 0.91 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL956149 0.91 TSHR (0.73) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111171761-B Adhesive composition, and adhesive film and surface protective film using same 藤森工业株式会社 2022-10-04 CN claimed
US-20130316137-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-28 US claimed
US-8530572-B2 Brightness enhancing film comprising nanocomposite structure having improved crack resistance 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-10 US claimed
US-20120264899-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY 2012-10-18 US claimed
EP-2118149-B1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES CO (US) 2012-05-23 EP claimed
JP-2010519599-A 2010-06-03 JP claimed
US-20100033826-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 US claimed
EP-2118149-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M Innovative Properties Company (US) 2009-11-18 EP claimed
WO-2008121465-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-09 WO claimed
US-5883212-A CATIONIC POLYMER WITH QUATERNARY AMMONIUM UNSATURATED MONOMER AND HYDROXYALKYL (METH)ACRYLATE AND/OR CYANOALKYL (METH)ACRYLATE COMONOMERS REXAM GRAPHICS, INC. (US) 1999-03-16 US claimed
EP-0301404-B1 GRAFT POLYMERS FROM POLYPHENYLENE ETHERS BASF Aktiengesellschaft (DE) 1992-03-18 EP claimed
US-4275142-A CONJUGATED DIOLEFIN-ACRYLIC ACID OR ANHYDRIDE COPOLYMER, PHOTOSENSITIZER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-06-23 US claimed
US-12637531-B2 Pigment dispersant composition, production method therefor, pigment dispersion, and actinic-ray-curable ink-jet ink DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2026-05-26 US disclosed
CN-116615332-B Optically anisotropic laminate and optical element MITSUBISHI CHEMICAL CORP. (JP) 2026-05-26 CN disclosed
EP-4347710-B1 MIXER SYSTEM FOR PRODUCING AQUEOUS COATING MATERIALS BASF COATINGS GMBH (DE) 2026-05-13 EP disclosed
US-12582745-B2 Adhesive composition for hard tissue repair JIAXING JINGYIN BIOTECHNOLOGY CO., LTD (CN) 2026-03-24 US disclosed
US-5134175-A Rapid curing high solids mixture of unsaturated prepolymers and monomers, photoinitiators, fillers, surfactants; for protective coatings, printing inks MLT/MICRO-LITE TECHNOLOGY CORPORATION 1992-07-28 US disclosed
US-4990428-A Photopolymerizable compound overcoating aluminum(or alloy therof), and aluminum oxide layers MITSUBISHI KASEI CORPORATION (JP) 1991-02-05 US disclosed
EP-0179448-B1 PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE MITSUBISHI KASEI CORPORATION (JP) 1990-04-18 EP disclosed
US-4275142-A CONJUGATED DIOLEFIN-ACRYLIC ACID OR ANHYDRIDE COPOLYMER, PHOTOSENSITIZER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637531-B2 Pigment dispersant composition, production method therefor, pigment dispersion, and actinic-ray-curable ink-jet ink VCL, DYNLL1, DYNLL2 TSHR 4380/4885ALDH1A1 253/4885TP53 1294/4885
US-12582745-B2 Adhesive composition for hard tissue repair PTK2, COL2A1, ILK TSHR 4305/4885ALDH1A1 1309/4885TP53 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.