SCHEMBL448700

SCHEMBL448700

CC(C)CC(=O)C(=O)Cc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.68
CES1 P23141 2/20 0.68
FNTA P49354 2/20 0.57
FNTB P49356 2/20 0.57
TSHR P16473 1/20 0.52
AKR1B1 P15121 1/20 0.50
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 1/20 0.46
PSMB8 P28062 1/20 0.45
PSMB5 P28074 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
POLB P06746 1/20 0.45
MEN1 O00255 2/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
SLC6A2 P23975 1/20 0.44
CNR2 P34972 1/20 0.44
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574185 0.82 CES1 (1.00) CES2CES1FNTAFNTBTSHR
SCHEMBL106957 0.82 FNTA (0.60) CES2CES1FNTAFNTBSLC6A2
SCHEMBL106992 0.82 TSHR (0.53) CES2CES1TSHRAKR1B1ALDH1A1
Phenylpyruvate SCHEMBL9753545 0.81 CES2 (0.48) CES2CES1FNTAFNTBTSHR
Hydrochloric Acid SCHEMBL3111570 0.80 CES1 (0.94) CES2CES1FNTAFNTBTSHR
Phenylacetic Acid SCHEMBL28235727 0.80 AKR1B1 (0.68) CES2CES1TSHRAKR1B1ALDH1A1
SCHEMBL9354964 0.78 TSHR (0.50) CES2CES1TSHRAKR1B1ALDH1A1
SCHEMBL9355881 0.78 TSHR (0.50) CES2CES1TSHRAKR1B1ALDH1A1
SCHEMBL451546 0.78 CES1 (0.64) CES2CES1FNTAFNTBTSHR
SCHEMBL21828466 0.77 TSHR (0.49) CES2CES1TSHRAKR1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
WO-2009097346-A2 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-06 WO disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
EP-0167174-B1 MIXTURES OF STABILIZERS FOR VINYL CHLORIDE POLYMER RESINS LONZA AG (CH) 1989-11-02 EP disclosed
US-4717747-A 3,5-DIKETOTETRAHYDROPYRAN-2,4,6-TRIONE, ALIPHATIC OR AROMATIC ACID SALT LONZA LTD. (CH) 1988-01-05 US disclosed
EP-0167174-A2 Mixtures of stabilizers for vinyl chloride polymer resins LONZA AG (CH) 1986-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA CES2 60/4885CES1 73/4885FNTA 1376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.