Sugi Predict

Sugi Predict / Compounds / SCHEMBL574185

SCHEMBL574185

SCHEMBL574185

O=C(Cc1ccccc1)C(=O)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 3/20 1.00
▸ CES2 O00748 2/20 1.00
▸ FNTA P49354 2/20 0.77
▸ FNTB P49356 2/20 0.77
▸ AKR1B1 P15121 1/20 0.70
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ HDAC8 Q9BY41 1/20 0.58
▸ HDAC6 Q9UBN7 1/20 0.58
▸ SLC6A2 P23975 1/20 0.55
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ CTBP2 P56545 1/20 0.54
▸ EPHX2 P34913 1/20 0.54
▸ TSHR P16473 2/20 0.52
▸ ABCC4 O15439 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ GAA P10253 1/20 0.52
▸ PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3111570 0.97 CES1 (0.94) CES1CES2FNTAFNTBAKR1B1
SCHEMBL4645081 0.90 CES1 (0.81) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28203540 0.89 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
SCHEMBL7003190 0.89 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL43235 0.89 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
SCHEMBL7195303 0.88 CES1 (0.77) CES1CES2FNTAFNTBAKR1B1
SCHEMBL4646048 0.88 CES1 (0.77) CES1CES2FNTAFNTBAKR1B1
SCHEMBL108976 0.88 CES1 (0.77) CES1CES2FNTAFNTBAKR1B1
Kurasoin A SCHEMBL30799774 0.88 FNTA (1.00) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL11193388 0.87 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 — — CN claimed
US-8951961-B2 Structural and mechanistic basis for novel compound biosynthesis using 4-electron hexose oxidase ACADEMIA SINICA (TW) 2015-02-10 — — US claimed
EP-2160397-B1 A NOVEL AND HIGHLY STEREOSELECTIVE PROCESS FOR PREPARING GEMCITABINE AND INTERMEDIATES THEREOF NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD (CN) 2014-03-26 — — EP claimed
CN-103497287-A Synthetic technology of epoxy vinyl ester resin for SMC/BMC HUACHANG POLYMER CO LTD OF ECUST 2014-01-08 — — CN claimed
US-20130288955-A1 STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING 4-ELECTRON HEXOSE OXIDASE ACADEMIA SINICA (TW) 2013-10-31 — — US claimed
CN-102504490-B Injection moldable electric epoxy molding plastic and preparation method thereof GUILIN ELECTRICAL EQUIPMENT SCIENTIFIC RES INST 2013-06-26 — — CN claimed
US-20130018181-A1 Novel and Highly Stereoselective Process for Preparing Gemcitabine and Intermediates Thereof Nanjing Cavendish Bio-Engineering Technology Co., Ltd. (CN) 2013-01-17 — — US claimed
CN-102153837-B High-performance high-temperature-resistant modified epoxy resin SHANGHAI MASTECK ECOLOGY SCIENCE TECHNOLOGY CO LTD 2012-09-05 — — CN claimed
US-20120108498-A1 STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING THE 4-ELECTRON HEXOSE OXIDASE ACADEMIA SINICA (TW) 2012-05-03 — — US claimed
US-7807750-B2 Thermally-reactive polymers SURMODICS, INC. (US) 2010-10-05 — — US claimed
US-5310745-A Acylated derivatives of 1,5-dideoxy-1,5-imino-D-glucitol, AIDS G. D. SEARLE & CO. (US) 1994-05-10 — — US claimed
US-5047397-A Natriuretics, diuretics, vasodilators CALIFORNIA BIOTECHNOLOGY INC. (US) 1991-09-10 — — US claimed
EP-0410989-A4 CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES — 1991-06-05 — — EP claimed
US-5003072-A Viricides G. D. SEARLE & CO. (US) 1991-03-26 — — US claimed
EP-0410989-A1 CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES CALIFORNIA BIOTECHNOLOGY, INC. (US) 1991-02-06 — — EP claimed
US-4935492-A Cyclic analogs of atrial natriuretic peptides CALIFORNIA BIOTECHNOLOGY INC. (US) 1990-06-19 — — US claimed
EP-0367748-A2 Novel antiviral compounds G.D. SEARLE & COMPANY (US) 1990-05-09 — — EP claimed
WO-1989009611-A1 CYCLIC ANALOGS OF ATRIAL NATRIURETIC PEPTIDES CALIFORNIA BIOTECHNOLOGY INC. (US) 1989-10-19 — — WO claimed
EP-0323740-A2 Linear analogs of atrial natriuretic peptides CALIFORNIA BIOTECHNOLOGY, INC. (US) 1989-07-12 — — EP claimed
WO-1989005654-A1 LINEAR ANALOGS OF ATRIAL NATRIURETIC PEPTIDES CALIFORNIA BIOTECHNOLOGY INC. (US) 1989-06-29 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108498-A1 STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING THE 4-ELECTRON HEXOSE OXIDASE G6PD, DHRS9, CYP2C9 CES1 768/4885CES2 713/4885FNTA 1279/4885
US-20130018181-A1 Novel and Highly Stereoselective Process for Preparing Gemcitabine and Intermediates Thereof KRAS, TYMP, TYMS CES1 1337/4885CES2 1520/4885FNTA 980/4885
US-20130288955-A1 STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING 4-ELECTRON HEXOSE OXIDASE G6PD, CYP4X1, UGT1A9 CES1 757/4885CES2 703/4885FNTA 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.