SCHEMBL448714

SCHEMBL448714

O=C1CC(=O)C2C3C=CC(C3)C12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 2/20 0.50
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
RECQL P46063 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 3/20 0.39
USP2 O75604 2/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MAPT P10636 1/20 0.37
POLB P06746 1/20 0.36
PKM P14618 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432513 1.00 ALDH1A1 (0.50) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL449523 0.83 POLB (0.42) ALDH1A1TDP1KMT2ARECQLL3MBTL1
SCHEMBL15203373 0.83 ALDH1A1 (0.50) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL431044 0.83 POLB (0.42) ALDH1A1TDP1KMT2ARECQLL3MBTL1
SCHEMBL12691989 0.79 ALDH1A1 (0.38) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL8139841 0.77 ALDH1A1 (0.54) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL14338369 0.72 ALDH1A1 (0.50) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL2386798 0.72 ALDH1A1 (0.50) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL6125172 0.72 ALDH1A1 (0.50) ALDH1A1TDP1RAB9AMEN1KMT2A
SCHEMBL7032560 0.72 ALDH1A1 (0.41) ALDH1A1TDP1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034341-A1 METHODS FOR INCORPORATING DYNAMIC BONDS INTO EXISTING POLYMERS NORTHWESTERN UNIVERSITY 2025-01-30 US disclosed
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-20210347935-A1 POLYMERS FOR SPECIALTY APPLICATIONS ExxonMobil Product Solutions Company 2021-11-11 US disclosed
WO-2020053357-A1 FUNCTIONAL POLYSILOXANES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2020-03-19 WO disclosed
US-9278909-B2 Amide-extended crosslinking compounds and methods for use thereof DESIGNER MOLECULES, INC. (US) 2016-03-08 US disclosed
US-8808804-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2014-08-19 US disclosed
US-20130228901-A1 MATERIALS AND METHODS FOR STRESS REDUCTION IN SEMICONDUCTOR WAFER PASSIVATION LAYERS DESIGNER MOLECULES, INC. (US) 2013-09-05 US disclosed
US-8513375-B2 Imide-linked maleimide and polymaleimide compounds DESIGNER MOLECULES, INC. 2013-08-20 US disclosed
US-20130101742-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY (US) 2013-04-25 US disclosed
EP-2429979-A1 NOVEL HERBICIDES Syngenta Limited (GB) 2012-03-21 EP disclosed
US-20120065066-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-03-15 US disclosed
US-20110130485-A1 IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS DESIGNER MOLECULES, INC. (US) 2011-06-02 US disclosed
US-7884174-B2 condensation of appropriate anhydrides with appropriate diamines to give amine terminated compounds, then condensed with excess maleic anhydride to yield imide-extended maleimide compounds DESIGNER MOLECULES, INC. (US) 2011-02-08 US disclosed
WO-2010133232-A1 NOVEL HERBICIDES SYNGENTA LIMITED (GB) 2010-11-25 WO disclosed
US-7452571-B2 Method of sealing semiconductor element mounted on gold-plated printed circuit board SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-11-18 US disclosed
US-20080075961-A1 Imide-linked maleimide and polymaleimide compounds DESIGNER MOLECULES, INC. 2008-03-27 US disclosed
US-20070104872-A1 METHOD OF SEALING SEMICONDUCTOR ELEMENT MOUNTED ON GOLD-PLATED PRINTED CIRCUIT BOARD SHIN -ETSU CHEMICAL CO., LTD. (JP) 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130485-A1 IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS MEN1, PBRM1, PAICS ALDH1A1 3665/4885TDP1 2833/4885RAB9A 2707/4885
US-20120065066-A1 NOVEL HERBICIDES DDT, CYP4X1, CYP1B1 ALDH1A1 14/4885TDP1 1576/4885RAB9A 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.