Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431044 | 1.00 | POLB (0.42) | POLBALDH1A1TDP1L3MBTL1APEX1 | |
| SCHEMBL432513 | 0.83 | ALDH1A1 (0.50) | POLBALDH1A1TDP1L3MBTL1RECQL | |
| SCHEMBL448714 | 0.83 | ALDH1A1 (0.50) | POLBALDH1A1TDP1L3MBTL1RECQL | |
| SCHEMBL20561319 | 0.77 | POLB (0.45) | POLBALDH1A1TDP1L3MBTL1APEX1 | |
| SCHEMBL2545104 | 0.72 | POLB (0.42) | POLBALDH1A1TDP1L3MBTL1APEX1 | |
| SCHEMBL14116733 | 0.71 | ALDH1A1 (0.42) | POLBALDH1A1KMT2A | |
| SCHEMBL4488756 | 0.70 | POLB (0.41) | POLBALDH1A1TDP1L3MBTL1APEX1 | |
| SCHEMBL2512784 | 0.70 | TDP1 (0.48) | POLBALDH1A1TDP1L3MBTL1APEX1 | |
| SCHEMBL21117867 | 0.70 | TDP1 (0.48) | POLBALDH1A1TDP1L3MBTL1APEX1 | |
| SCHEMBL5833458 | 0.70 | TDP1 (0.48) | POLBALDH1A1TDP1L3MBTL1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429979-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | POLB 4374/4885ALDH1A1 14/4885TDP1 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.