Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.72 |
| ▸ | PPARG | P37231 | 3/20 | 0.72 |
| ▸ | PPARD | Q03181 | 3/20 | 0.72 |
| ▸ | PPARA | Q07869 | 3/20 | 0.72 |
| ▸ | TOP1 | P11387 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | FABP4 | P15090 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | FAAH | O00519 | 2/20 | 0.72 |
| ▸ | F7 | P08709 | 2/20 | 0.72 |
| ▸ | F3 | P13726 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.72 |
| ▸ | GMNN | O75496 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28236949 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27946115 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27977050 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL28401623 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL29159701 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27928166 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL29431318 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL28365304 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL28907994 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27928102 | 1.00 | TERT (0.72) | TERTPTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507854-B2 | Impurity reduction in Olefin metathesis reactions | MATERIA, INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-20050203324-A1 | Impurity reduction in Olefin metathesis reactions | MATERIA, INC. | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203324-A1 | Impurity reduction in Olefin metathesis reactions | CYP51A1, COASY, ECI1 | TERT 3815/4885PTPN1 4095/4885PPARG 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.